EVALUATION OF THE APPLICABILITY OF A CHILD-APPROPRIATE HIGH THROUGHPUT HPLC-MS/MS METHOD FOR THE DETERMINATION OF ENALAPRIL AND ENALAPRILAT IN SMALL SAMPLE VOLUMES OF SERUM AND URINE WITHIN A GCLP-COMPLIANT ENVIRONMENT

BackgroundHeart failure is a life-threatening disease in neonates up to adolescents. The angiotensin-converting enzyme inhibitor enalapril is a recommended therapy in paediatric heart failure, although it is not labelled for patients Objective: Proof of concept of the paediatric tailored assays by v...

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Veröffentlicht in:	Archives of disease in childhood 2016-01, Vol.101 (1), p.e1.69-e1
Hauptverfasser:	Schäfer, Julia, Burckhardt, Björn B., Tins, Jutta, Läer, Stephanie
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Care and treatment Dosage and administration Enalapril Enalaprilat Heart failure Practice guidelines (Medicine)
Online-Zugang:	Volltext
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