Regional hypoplasia of somatosensory cortex in growth-retarded mice (grt/grt)

Growth‐retarded mouse (grt/grt) is a spontaneous mutant that is known as an animal model for primary congenital hypothyroidism caused by resistance to TSH signaling. The regional pattern of cerebral cortical hypoplasia was characterized in grt/grt mice. Ex vivo computed tomography (CT)‐based volumet...

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Veröffentlicht in:	Congenital anomalies 2016-07, Vol.56 (4), p.180-183
Hauptverfasser:	Sawada, Kazuhiko, Saito, Shigeyoshi, Sugasawa, Akari, Sato, Chika, Aoyama, Junya, Ohara, Naoko, Horiuchi-Hirose, Miwa, Kobayashi, Tetsuya
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals computed tomography Cone-Beam Computed Tomography Congenital diseases Congenital Hypothyroidism - diagnosis Congenital Hypothyroidism - genetics Developmental Disabilities - diagnosis Developmental Disabilities - genetics Disease Models, Animal Female growth-retarded mouse Hypothyroidism Male Mice Mice, Transgenic Phenotype somatosensory cortex Somatosensory Cortex - pathology volumetry X-Ray Microtomography
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