Human sLZIP promotes atherosclerosis via MMP‐9 transcription and vascular smooth muscle cell migration

Atherosclerosis is a chronic inflammatory response of the vascular wall, and immune responses are involved in every phase of atherosclerosis, from initiation, to progression, and finally to plaque rupture. Cytokines are the major atherogenic mediators that promote plaque formation and progression by...

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Veröffentlicht in:	The FASEB journal 2014-11, Vol.28 (11), p.5010-5021
Hauptverfasser:	Kim, Jeonghan, Ko, Jesang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals atherosclerosis Atherosclerosis - metabolism Cell Movement - physiology Cells, Cultured Cyclic AMP Response Element-Binding Protein - metabolism Gene Expression Regulation, Enzymologic Humans macrophage Macrophages - metabolism matrix metalloproteinase Matrix Metalloproteinase 9 - genetics Matrix Metalloproteinase 9 - metabolism Mice Muscle, Smooth, Vascular - cytology Myocytes, Smooth Muscle - metabolism sLZIP Transcription, Genetic Tumor Necrosis Factor-alpha - metabolism vascular smooth muscle cell
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