A novel method for high-throughput detection and quantification of neutrophil extracellular traps reveals ROS-independent NET release with immune complexes

Abstract A newly-described first-line immune defence mechanism of neutrophils is the release of neutrophil extracellular traps (NETs). Immune complexes (ICxs) induce low level NET release. As such, the in vitro quantification of NETs is challenging with current methodologies. In order to investigate...

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Veröffentlicht in:Autoimmunity reviews 2016-06, Vol.15 (6), p.577-584
Hauptverfasser: Kraaij, Tineke, Tengström, Fredrik C, Kamerling, Sylvia W.A, Pusey, Charles D, Scherer, H. Ulrich, Toes, Rene E.M, Rabelink, Ton J, van Kooten, Cees, Teng, Y.K. Onno
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Sprache:eng
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