Comparative repair capacity of knee osteochondral defects using regenerated silk fiber scaffolds and fibrin glue with/without autologous chondrocytes during 36 weeks in rabbit model

The reconstruction capability of osteochondral (OCD) defects using silk-based scaffolds has been demonstrated in a few studies. However, improvement in the mechanical properties of natural scaffolds is still challengeable. Here, we investigate the in vivo repair capacity of OCD defects using a novel...

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Veröffentlicht in:	Cell and tissue research 2016-06, Vol.364 (3), p.559-572
Hauptverfasser:	Kazemnejad, Somaieh, Khanmohammadi, Manijeh, Mobini, Sahba, Taghizadeh-Jahed, Masoud, Khanjani, Sayeh, Arasteh, Shaghayegh, Golshahi, Hannaneh, Torkaman, Giti, Ravanbod, Roya, Heidari-Vala, Hamed, Moshiri, Ali, Tahmasebi, Mohammad-Naghi, Akhondi, Mohammad-Mehdi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biocompatibility Biomechanical Phenomena - drug effects Biomedical and Life Sciences Biomedicine Bombyx mori Cartilage Cartilage, Articular - drug effects Cartilage, Articular - pathology Cartilage, Articular - physiopathology Chondrocytes - drug effects Chondrocytes - transplantation Collagen Type II - metabolism Disease Models, Animal EDTA Fibrin Fibrin Tissue Adhesive - pharmacology Hindlimb - drug effects Hindlimb - pathology Hindlimb - physiopathology Human Genetics Immunohistochemistry Joint and ligament injuries Knee Male Mechanical properties Medical research Mice, Inbred C57BL Molecular Medicine Porosity Prosthesis Implantation Proteomics Rabbits Regeneration Regular Article Silk Silk - pharmacology Subcutaneous Tissue - drug effects Subcutaneous Tissue - pathology Tissue engineering Tissue Scaffolds - chemistry Transplantation, Autologous Transplants & implants Wound Healing - drug effects
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