Electromechanical window negativity in genotyped long-QT syndrome patients: relation to arrhythmia risk

Prolonged and dispersed left-ventricular (LV) contraction is present in patients with long-QT syndrome (LQTS). Electrical and mechanical abnormalities appear most pronounced in symptomatic individuals. We focus on the 'electromechanical window' (EMW; duration of LV-mechanical systole minus...

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Veröffentlicht in:	European heart journal 2015-01, Vol.36 (3), p.179-186
Hauptverfasser:	ter Bekke, Rachel M A, Haugaa, Kristina H, van den Wijngaard, Arthur, Bos, J Martijn, Ackerman, Michael J, Edvardsen, Thor, Volders, Paul G A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - therapeutic use Adult Analysis of Variance Anti-Arrhythmia Agents - therapeutic use Arrhythmias, Cardiac - genetics Case-Control Studies Death, Sudden, Cardiac - prevention & control Electrocardiography ERG1 Potassium Channel Ether-A-Go-Go Potassium Channels - genetics Female Genotype Heterozygote Humans Ion Channels - genetics Ion Channels - physiology KCNQ1 Potassium Channel - genetics Long QT Syndrome - drug therapy Long QT Syndrome - genetics Long QT Syndrome - physiopathology Male Mutation - genetics NAV1.5 Voltage-Gated Sodium Channel - genetics Potassium Channels, Voltage-Gated - genetics Risk Factors Ultrasonography, Doppler
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