Expression of Androgen and Estrogen Signaling Components and Stem Cell Markers to Predict Cancer Progression and Cancer-Specific Survival in Patients with Metastatic Prostate Cancer

Genes of androgen and estrogen signaling cells and stem cell-like cells play crucial roles in prostate cancer. This study aimed to predict clinical failure by identifying these prostate cancer-related genes. We developed models to predict clinical failure using biopsy samples from a training set of...

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Veröffentlicht in:	Clinical cancer research 2014-09, Vol.20 (17), p.4625-4635
Hauptverfasser:	FUJIMURA, Tetsuya, TAKAHASHI, Satou, INOUE, Satoshi, HOMMA, Yukio, URANO, Tomohiko, TAKAYAMA, Kenichi, SUGIHARA, Toru, OBINATA, Daisuke, YAMADA, Yuta, KUMAGAI, Jimpei, KUME, Haruki, OUCHI, Yasuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Androgens - genetics Androgens - metabolism Antineoplastic agents Biological and medical sciences Biomarkers, Tumor Bone Neoplasms - genetics Bone Neoplasms - pathology Bone Neoplasms - secondary Disease-Free Survival Estrogens - genetics Estrogens - metabolism Gene Expression Regulation, Neoplastic Gynecology. Andrology. Obstetrics Humans Male Male genital diseases Medical sciences Middle Aged Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoplasm Grading Neoplastic Stem Cells Nephrology. Urinary tract diseases Pharmacology. Drug treatments Prognosis Prostate-Specific Antigen - genetics Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology Receptors, Androgen - biosynthesis Receptors, Estrogen - biosynthesis Tumors Tumors of the urinary system Urinary tract. Prostate gland
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