Acute kidney injury in patients with acute coronary syndromes

Acute kidney injury (AKI) is increasingly being seen in patients with acute coronary syndromes (ACSs). This condition has a complex pathogenesis, an incidence that can reach 30% and it is associated with higher short-term and long-term morbidity and mortality. Nevertheless, AKI is still characterise...

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Veröffentlicht in:Heart (British Cardiac Society) 2015-11, Vol.101 (22), p.1778-1785
Hauptverfasser: Marenzi, Giancarlo, Cosentino, Nicola, Bartorelli, Antonio L
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creator Marenzi, Giancarlo
Cosentino, Nicola
Bartorelli, Antonio L
description Acute kidney injury (AKI) is increasingly being seen in patients with acute coronary syndromes (ACSs). This condition has a complex pathogenesis, an incidence that can reach 30% and it is associated with higher short-term and long-term morbidity and mortality. Nevertheless, AKI is still characterised by lack of a single accepted definition, unclear pathophysiology understanding and insensitive diagnostic tools that make its detection difficult, particularly in the setting of ACS. Recent data suggested that patients with AKI during ACS, even those in whom renal function seems to fully recover, face an increased, persisting risk of future AKI and may develop chronic kidney disease. Thus, in these patients, nephrology follow-up, after hospital discharge, and secondary preventive measures should possibly be implemented. In this review, we aim at providing a framework of knowledge to increase cardiologists’ awareness of AKI, with the goal of improving the outcome of patients with ACS.
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This condition has a complex pathogenesis, an incidence that can reach 30% and it is associated with higher short-term and long-term morbidity and mortality. Nevertheless, AKI is still characterised by lack of a single accepted definition, unclear pathophysiology understanding and insensitive diagnostic tools that make its detection difficult, particularly in the setting of ACS. Recent data suggested that patients with AKI during ACS, even those in whom renal function seems to fully recover, face an increased, persisting risk of future AKI and may develop chronic kidney disease. Thus, in these patients, nephrology follow-up, after hospital discharge, and secondary preventive measures should possibly be implemented. 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subjects Acute Coronary Syndrome - blood
Acute Coronary Syndrome - complications
Acute coronary syndromes
Acute Kidney Injury - blood
Acute Kidney Injury - complications
Acute Kidney Injury - diagnosis
Chronic Disease
Creatinine - metabolism
Disease Progression
Glomerular Filtration Rate - physiology
Heart attacks
Humans
Kidney Failure, Chronic - etiology
Mortality
Myocardial Infarction - complications
Prognosis
Studies
Terminology as Topic
title Acute kidney injury in patients with acute coronary syndromes
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