Hippocampal granule neuron production and population size are regulated by levels of bFGF

Numerous studies of the proliferative effects of basic fibroblast growth factor (bFGF) in culture, including neonatal and adult hippocampal precursors, suggest that the factor plays a ubiquitous and life‐long role in neurogenesis. In contrast, in vivo, bFGF is devoid of effects on neurons in mature...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The European journal of neuroscience 2002-01, Vol.15 (1), p.3-12
Hauptverfasser:	Cheng, Yinghong, Black, Ira B., DiCicco-Bloom, Emanuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Algorithms Animals Animals, Newborn Antimetabolites bFGF bFGF deletion mutants Bromodeoxyuridine Cell Count Cell Size - drug effects Cytoplasmic Granules - drug effects Cytoplasmic Granules - ultrastructure dentate gyrus Dentate Gyrus - drug effects Dentate Gyrus - ultrastructure DNA - biosynthesis DNA - genetics Fibroblast Growth Factor 2 - genetics Fibroblast Growth Factor 2 - pharmacology hippocampus Hippocampus - cytology Hippocampus - drug effects Hippocampus - ultrastructure Immunohistochemistry Male Mice Mice, Knockout Mutation neurogenesis Neuroglia - physiology neuron production neuronal precursors neuronogenesis Neurons - drug effects Neurons - ultrastructure newborn rats proliferation Rats Rats, Sprague-Dawley stereology Thymidine - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!