PS-147Ultrasound Cardiac Output Monitoring (uscom) In Mechanically Ventilated Critically Ill Children

Background and aimsHaemodynamic monitoring plays an important role in the management of critically ill patients. The goal of this study was to evaluate haemodynamic changes within first 48 h after initiation of mechanical ventilation (MV).MethodsCritically ill children were included and divided into two groups according to the indication for MV. Group A ventilated for pulmonary pathology (P), group B ventilated for non pulmonary pathology (NP). Noninvasive haemodynamic monitoring (USCOM) was used in both groups after the initiation of MV (Time 1) and at 6, 12 and 48 h intervals (Time 2, 3, 4). Parameters such as CI, SVRI, SVI, SBP and DBP were analysed. Strategies of protective MV were applied in both groups.ResultsGroup A included 36 children, mean age 44 months. Group B included 13 children, mean age 58 months. The comparisons within the groups and between the groups are presented in Table 1.Abstract PS-147 Table 1 Pulmonary group - P Non pulmonary group - NP Time 1 Time 4 comparison Time 1 Time 4 comparison CI 4.30 plus or minus 1.254.09 plus or minus 1.08NS4.33 plus or minus 1.573.59 plus or minus 1.03NS SVRI 1193 plus or minus 5921321 plus or minus 557NS1050 plus or minus 1931607 plus or minus 570p < 0.005 SVI 34 plus or minus 1135 plus or minus 11NS36 plus or minus 1237 plus or minus 12NS SBP 90 plus or minus 21102 plus or minus 25p < 0.014287 plus or minus 21102 plus or minus 19p < 0.0251 DBP 52 plus or minus 1556 plus or minus 17NS47 plus or minus 1555 plus or minus 17NSp < 0.05 was considered statistically significant.ConclusionsSVRI increased during first 48 h of ventilation in NP group, SBP increased in both groups. No other clinically significant haemodynamic changes in either group were found.AcknowledgementsThe work was supported by project PRVOUK P-36.