Interleukin-1β Suppresses the Transporter Genes Ank and Ent1 Expression in Stromal Progenitor Cells Retaining Mineralization

Heterotopic ossification (HO) in various tissues evokes clinical problems. Inflammatory responses of the stromal progenitor cells may be involved in its etiology. Previous report indicated that pro-inflammatory cytokines including IL-1β enhanced the in vitro calcification of human mesenchymal stem c...

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Veröffentlicht in:	Calcified tissue international 2016-08, Vol.99 (2), p.199-208
Hauptverfasser:	Ezura, Yoichi, Lin, Xin, Hatta, Arina, Izu, Yayoi, Noda, Masaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biomedical and Life Sciences Calcification, Physiologic - drug effects Calcification, Physiologic - physiology Calcinosis - metabolism Cell Biology Cell Differentiation - drug effects Cell Differentiation - physiology Cells, Cultured Endocrinology Equilibrative Nucleoside Transporter 1 - metabolism Humans Interleukin-1beta - metabolism Interleukin-1beta - pharmacology Life Sciences Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - drug effects Mice Original Research Orthopedics Osteogenesis - drug effects Osteogenesis - physiology Phosphate Transport Proteins - metabolism Stem Cells - drug effects Stem Cells - metabolism Stromal Cells - cytology Stromal Cells - drug effects
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