An Ideal PPAR Response Element Bound to and Activated by PPAR[alpha]

Peroxisome proliferator-activated receptor-[alpha] (PPAR[alpha]), a nuclear receptor, plays an important role in the transcription of genes involved in fatty acid metabolism through heterodimerization with the retinoid x receptor (RXR). The consensus sequence of the PPAR response element (PPRE) is c...

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Veröffentlicht in:PloS one 2015-08, Vol.10 (8)
Hauptverfasser: Tzeng, John, Byun, Jaemin, Park, Ji Yeon, Yamamoto, Takanobu, Schesing, Kevin, Tian, Bin, Sadoshima, Junichi, Oka, Shin-ichi
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Sprache:eng
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