Leukocyte‐associated Ig‐like receptor‐1 is a novel inhibitory receptor for surfactant protein D

Inhibitory LAIR‐1 as a novel receptor for SP‐D, and may mediate immunomodulatory effects of SP‐D. The collagenous C‐type lectin, SP‐D, is a multitrimeric glycoprotein present at mucosal surfaces and is involved in host defense against infections in mammals. SP‐D has immunomodulatory properties, but...

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Veröffentlicht in:	Journal of leukocyte biology 2014-07, Vol.96 (1), p.105-111
Hauptverfasser:	Olde Nordkamp, Marloes J. M., Eijk, Martin, Urbanus, Rolf T., Bont, Louis, Haagsman, Henk P., Meyaard, Linde
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - genetics Antigens, CD - immunology Antigens, CD - metabolism collectin HL-60 Cells Humans immunomodulatory inhibitory immune receptor LAIR‐1 Protein Binding Protein Structure, Tertiary Pulmonary Surfactant-Associated Protein D - genetics Pulmonary Surfactant-Associated Protein D - immunology Pulmonary Surfactant-Associated Protein D - metabolism Receptors, Fc - genetics Receptors, Fc - immunology Receptors, Fc - metabolism Receptors, Immunologic - agonists Receptors, Immunologic - genetics Receptors, Immunologic - immunology Receptors, Immunologic - metabolism
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