Cutaneous Manifestations of Multiple Myeloma and Other Plasma Cell Proliferative Disorders
Plasma cell proliferative disorders cause rare but extremely varied dermatologic manifestations that may occur as an accompaniment to established diagnoses, or may be a first clue of an underlying neoplasm in the setting of clinical suspicion. In some instances skin lesions result from aggregation o...
Gespeichert in:
| Veröffentlicht in: | Seminars in oncology 2016-06, Vol.43 (3), p.395-400 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 400 |
|---|---|
| container_issue | 3 |
| container_start_page | 395 |
| container_title | Seminars in oncology |
| container_volume | 43 |
| creator | Bhutani, Manisha, MD Shahid, Zainab, MD Schnebelen, Alicia, MD Alapat, Daisy, MD Usmani, Saad Z., MD, FACP |
| description | Plasma cell proliferative disorders cause rare but extremely varied dermatologic manifestations that may occur as an accompaniment to established diagnoses, or may be a first clue of an underlying neoplasm in the setting of clinical suspicion. In some instances skin lesions result from aggregation of misfolded monoclonal immunoglobulins or their fragments, as in light-chain related systemic amyloidosis. In other occasions the cutaneous lesions result from deposits of malignant plasma cells or monoclonal proteins. In still others, the dermatologic manifestations are related to antibody activity of monoclonal protein, as in many cases of cryoglobulinemia. This report provides insights into the well-recognized cutaneous manifestations associated with plasma cell disorders. |
| doi_str_mv | 10.1053/j.seminoncol.2016.02.017 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1808652914</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0093775416000427</els_id><sourcerecordid>1789045026</sourcerecordid><originalsourceid>FETCH-LOGICAL-c462t-e63b72cb6ca4452e61a25f1ab8498fc51b719a596945280ace62e3a69b23669e3</originalsourceid><addsrcrecordid>eNqNkkuLFDEUhYMoTjv6FyRLN1XepCqP2gja4wummQF14yakUrcwbarSJlUD_e9N06OCG10Fwvnu45xLCGVQMxDNy32dcfJznF0MNQcma-A1MPWAbJhoeKUV6IdkA9A1lVKivSBPct4DcKY4f0wuuGJKy67dkK_bdbEzxjXTnZ39iHmxi49zpnGkuzUs_hCQ7o4Y4mSpnQd6s3zDRG-DzeVjiyHQ2xRDIVMB75Be-RzTgCk_JY9GGzI-u38vyZd3bz9vP1TXN-8_bl9fV66VfKlQNr3irpfOtq3gKJnlYmS2122nRydYr1hnRVfGFVyDdSg5NlZ2PW-k7LC5JC_OdQ8p_ljLAmby2ZXBznsZpkFLwTvW_luqdAetAC6LVJ-lLsWcE47mkPxk09EwMKcQzN78CcGcQjDATQmhoM_vu6z9hMNv8JfrRfDmLMBiy53HZLLzODscfEK3mCH6_-ny6q8iLvjZOxu-4xHzPq5pLrYbZnIBzKfTMZxugUkAaLlqfgKbdLJv</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1789045026</pqid></control><display><type>article</type><title>Cutaneous Manifestations of Multiple Myeloma and Other Plasma Cell Proliferative Disorders</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Bhutani, Manisha, MD ; Shahid, Zainab, MD ; Schnebelen, Alicia, MD ; Alapat, Daisy, MD ; Usmani, Saad Z., MD, FACP</creator><creatorcontrib>Bhutani, Manisha, MD ; Shahid, Zainab, MD ; Schnebelen, Alicia, MD ; Alapat, Daisy, MD ; Usmani, Saad Z., MD, FACP</creatorcontrib><description>Plasma cell proliferative disorders cause rare but extremely varied dermatologic manifestations that may occur as an accompaniment to established diagnoses, or may be a first clue of an underlying neoplasm in the setting of clinical suspicion. In some instances skin lesions result from aggregation of misfolded monoclonal immunoglobulins or their fragments, as in light-chain related systemic amyloidosis. In other occasions the cutaneous lesions result from deposits of malignant plasma cells or monoclonal proteins. In still others, the dermatologic manifestations are related to antibody activity of monoclonal protein, as in many cases of cryoglobulinemia. This report provides insights into the well-recognized cutaneous manifestations associated with plasma cell disorders.</description><identifier>ISSN: 0093-7754</identifier><identifier>EISSN: 1532-8708</identifier><identifier>DOI: 10.1053/j.seminoncol.2016.02.017</identifier><identifier>PMID: 27178694</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Amyloidosis - pathology ; Cryoglobulinemia - pathology ; Dermatologic ; Hematology, Oncology and Palliative Medicine ; Humans ; Multiple Myeloma - pathology ; Myeloma ; Myeloproliferative Disorders - pathology ; Plasma cell dyscrasias ; Plasma Cells - pathology ; Plasmacytoma - pathology ; Plasmacytoma - secondary ; POEMS Syndrome - pathology ; Schnitzler Syndrome - pathology ; Scleromyxedema - pathology ; Skin ; Skin Diseases, Infectious - pathology ; Skin Neoplasms - pathology ; Skin Neoplasms - secondary ; Xanthomatosis - pathology</subject><ispartof>Seminars in oncology, 2016-06, Vol.43 (3), p.395-400</ispartof><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c462t-e63b72cb6ca4452e61a25f1ab8498fc51b719a596945280ace62e3a69b23669e3</citedby><cites>FETCH-LOGICAL-c462t-e63b72cb6ca4452e61a25f1ab8498fc51b719a596945280ace62e3a69b23669e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1053/j.seminoncol.2016.02.017$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27178694$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bhutani, Manisha, MD</creatorcontrib><creatorcontrib>Shahid, Zainab, MD</creatorcontrib><creatorcontrib>Schnebelen, Alicia, MD</creatorcontrib><creatorcontrib>Alapat, Daisy, MD</creatorcontrib><creatorcontrib>Usmani, Saad Z., MD, FACP</creatorcontrib><title>Cutaneous Manifestations of Multiple Myeloma and Other Plasma Cell Proliferative Disorders</title><title>Seminars in oncology</title><addtitle>Semin Oncol</addtitle><description>Plasma cell proliferative disorders cause rare but extremely varied dermatologic manifestations that may occur as an accompaniment to established diagnoses, or may be a first clue of an underlying neoplasm in the setting of clinical suspicion. In some instances skin lesions result from aggregation of misfolded monoclonal immunoglobulins or their fragments, as in light-chain related systemic amyloidosis. In other occasions the cutaneous lesions result from deposits of malignant plasma cells or monoclonal proteins. In still others, the dermatologic manifestations are related to antibody activity of monoclonal protein, as in many cases of cryoglobulinemia. This report provides insights into the well-recognized cutaneous manifestations associated with plasma cell disorders.</description><subject>Amyloidosis - pathology</subject><subject>Cryoglobulinemia - pathology</subject><subject>Dermatologic</subject><subject>Hematology, Oncology and Palliative Medicine</subject><subject>Humans</subject><subject>Multiple Myeloma - pathology</subject><subject>Myeloma</subject><subject>Myeloproliferative Disorders - pathology</subject><subject>Plasma cell dyscrasias</subject><subject>Plasma Cells - pathology</subject><subject>Plasmacytoma - pathology</subject><subject>Plasmacytoma - secondary</subject><subject>POEMS Syndrome - pathology</subject><subject>Schnitzler Syndrome - pathology</subject><subject>Scleromyxedema - pathology</subject><subject>Skin</subject><subject>Skin Diseases, Infectious - pathology</subject><subject>Skin Neoplasms - pathology</subject><subject>Skin Neoplasms - secondary</subject><subject>Xanthomatosis - pathology</subject><issn>0093-7754</issn><issn>1532-8708</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkkuLFDEUhYMoTjv6FyRLN1XepCqP2gja4wummQF14yakUrcwbarSJlUD_e9N06OCG10Fwvnu45xLCGVQMxDNy32dcfJznF0MNQcma-A1MPWAbJhoeKUV6IdkA9A1lVKivSBPct4DcKY4f0wuuGJKy67dkK_bdbEzxjXTnZ39iHmxi49zpnGkuzUs_hCQ7o4Y4mSpnQd6s3zDRG-DzeVjiyHQ2xRDIVMB75Be-RzTgCk_JY9GGzI-u38vyZd3bz9vP1TXN-8_bl9fV66VfKlQNr3irpfOtq3gKJnlYmS2122nRydYr1hnRVfGFVyDdSg5NlZ2PW-k7LC5JC_OdQ8p_ljLAmby2ZXBznsZpkFLwTvW_luqdAetAC6LVJ-lLsWcE47mkPxk09EwMKcQzN78CcGcQjDATQmhoM_vu6z9hMNv8JfrRfDmLMBiy53HZLLzODscfEK3mCH6_-ny6q8iLvjZOxu-4xHzPq5pLrYbZnIBzKfTMZxugUkAaLlqfgKbdLJv</recordid><startdate>20160601</startdate><enddate>20160601</enddate><creator>Bhutani, Manisha, MD</creator><creator>Shahid, Zainab, MD</creator><creator>Schnebelen, Alicia, MD</creator><creator>Alapat, Daisy, MD</creator><creator>Usmani, Saad Z., MD, FACP</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7T5</scope><scope>H94</scope></search><sort><creationdate>20160601</creationdate><title>Cutaneous Manifestations of Multiple Myeloma and Other Plasma Cell Proliferative Disorders</title><author>Bhutani, Manisha, MD ; Shahid, Zainab, MD ; Schnebelen, Alicia, MD ; Alapat, Daisy, MD ; Usmani, Saad Z., MD, FACP</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c462t-e63b72cb6ca4452e61a25f1ab8498fc51b719a596945280ace62e3a69b23669e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Amyloidosis - pathology</topic><topic>Cryoglobulinemia - pathology</topic><topic>Dermatologic</topic><topic>Hematology, Oncology and Palliative Medicine</topic><topic>Humans</topic><topic>Multiple Myeloma - pathology</topic><topic>Myeloma</topic><topic>Myeloproliferative Disorders - pathology</topic><topic>Plasma cell dyscrasias</topic><topic>Plasma Cells - pathology</topic><topic>Plasmacytoma - pathology</topic><topic>Plasmacytoma - secondary</topic><topic>POEMS Syndrome - pathology</topic><topic>Schnitzler Syndrome - pathology</topic><topic>Scleromyxedema - pathology</topic><topic>Skin</topic><topic>Skin Diseases, Infectious - pathology</topic><topic>Skin Neoplasms - pathology</topic><topic>Skin Neoplasms - secondary</topic><topic>Xanthomatosis - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bhutani, Manisha, MD</creatorcontrib><creatorcontrib>Shahid, Zainab, MD</creatorcontrib><creatorcontrib>Schnebelen, Alicia, MD</creatorcontrib><creatorcontrib>Alapat, Daisy, MD</creatorcontrib><creatorcontrib>Usmani, Saad Z., MD, FACP</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Seminars in oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bhutani, Manisha, MD</au><au>Shahid, Zainab, MD</au><au>Schnebelen, Alicia, MD</au><au>Alapat, Daisy, MD</au><au>Usmani, Saad Z., MD, FACP</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cutaneous Manifestations of Multiple Myeloma and Other Plasma Cell Proliferative Disorders</atitle><jtitle>Seminars in oncology</jtitle><addtitle>Semin Oncol</addtitle><date>2016-06-01</date><risdate>2016</risdate><volume>43</volume><issue>3</issue><spage>395</spage><epage>400</epage><pages>395-400</pages><issn>0093-7754</issn><eissn>1532-8708</eissn><abstract>Plasma cell proliferative disorders cause rare but extremely varied dermatologic manifestations that may occur as an accompaniment to established diagnoses, or may be a first clue of an underlying neoplasm in the setting of clinical suspicion. In some instances skin lesions result from aggregation of misfolded monoclonal immunoglobulins or their fragments, as in light-chain related systemic amyloidosis. In other occasions the cutaneous lesions result from deposits of malignant plasma cells or monoclonal proteins. In still others, the dermatologic manifestations are related to antibody activity of monoclonal protein, as in many cases of cryoglobulinemia. This report provides insights into the well-recognized cutaneous manifestations associated with plasma cell disorders.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27178694</pmid><doi>10.1053/j.seminoncol.2016.02.017</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0093-7754 |
| ispartof | Seminars in oncology, 2016-06, Vol.43 (3), p.395-400 |
| issn | 0093-7754 1532-8708 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1808652914 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Amyloidosis - pathology Cryoglobulinemia - pathology Dermatologic Hematology, Oncology and Palliative Medicine Humans Multiple Myeloma - pathology Myeloma Myeloproliferative Disorders - pathology Plasma cell dyscrasias Plasma Cells - pathology Plasmacytoma - pathology Plasmacytoma - secondary POEMS Syndrome - pathology Schnitzler Syndrome - pathology Scleromyxedema - pathology Skin Skin Diseases, Infectious - pathology Skin Neoplasms - pathology Skin Neoplasms - secondary Xanthomatosis - pathology |
| title | Cutaneous Manifestations of Multiple Myeloma and Other Plasma Cell Proliferative Disorders |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T11%3A49%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Cutaneous%20Manifestations%20of%20Multiple%20Myeloma%20and%20Other%20Plasma%20Cell%20Proliferative%20Disorders&rft.jtitle=Seminars%20in%20oncology&rft.au=Bhutani,%20Manisha,%20MD&rft.date=2016-06-01&rft.volume=43&rft.issue=3&rft.spage=395&rft.epage=400&rft.pages=395-400&rft.issn=0093-7754&rft.eissn=1532-8708&rft_id=info:doi/10.1053/j.seminoncol.2016.02.017&rft_dat=%3Cproquest_cross%3E1789045026%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1789045026&rft_id=info:pmid/27178694&rft_els_id=1_s2_0_S0093775416000427&rfr_iscdi=true |