Antifibrotic Actions of Serelaxin – New Roles for an Old Player

Fibrosis represents a failed wound healing response to tissue injury. It is characterized by the accumulation of excess connective tissue and is a significant cause of organ failure, morbidity, and mortality. Fibrotic disorders accompany a wide spectrum of conditions including both systemic and orga...

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Veröffentlicht in:	Trends in pharmacological sciences (Regular ed.) 2016-06, Vol.37 (6), p.485-497
Hauptverfasser:	Samuel, Chrishan S, Summers, Roger J, Hewitson, Tim D
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals collagen Drug Therapy, Combination fibrosis Fibrosis - drug therapy Fibrosis - pathology Humans Recombinant Proteins - administration & dosage Recombinant Proteins - pharmacology relaxin Relaxin - administration & dosage Relaxin - pharmacology serelaxin signal transduction TGF-β1 Wound Healing - drug effects
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