Management of congenital diaphragmatic hernia with transposition of the great arteries

Congenital diaphragmatic hernia (CDH) is a relatively rare malformation, but it has a high mortality rate. Its association with congenital heart disease lowers survival rate due to severe acidosis and desaturation caused by persistent pulmonary hypertension of the neonate. We describe herein a case...

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Veröffentlicht in:Pediatrics international 2016-06, Vol.58 (6), p.516-518
Hauptverfasser: Nagata, Hazumu, Yamamura, Kenichiro, Nagata, Kouji, Uike, Kiyoshi, Morihana, Eiji, Ihara, Kenji, Yumoto, Yasuo, Fusazaki, Naoki, Kado, Hideaki, Kato, Kiyoko, Taguchi, Tomoaki, Hara, Toshiro
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container_end_page 518
container_issue 6
container_start_page 516
container_title Pediatrics international
container_volume 58
creator Nagata, Hazumu
Yamamura, Kenichiro
Nagata, Kouji
Uike, Kiyoshi
Morihana, Eiji
Ihara, Kenji
Yumoto, Yasuo
Fusazaki, Naoki
Kado, Hideaki
Kato, Kiyoko
Taguchi, Tomoaki
Hara, Toshiro
description Congenital diaphragmatic hernia (CDH) is a relatively rare malformation, but it has a high mortality rate. Its association with congenital heart disease lowers survival rate due to severe acidosis and desaturation caused by persistent pulmonary hypertension of the neonate. We describe herein a case of CDH with transposition of the great arteries and intact ventricular septum, in a patient who was prenatally diagnosed, managed with extracorporeal oxygenation (ECMO) support and successfully treated with both CDH repair and Jatene procedure, with no respiratory or circulatory sequelae. In conclusion, precise prenatal estimation is essential, and ECMO is a useful therapeutic option in these complex cases.
doi_str_mv 10.1111/ped.12912
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source Wiley Online Library Journals Frontfile Complete
subjects Acidosis
Arteries
Cardiovascular disease
Complications
congenital diaphragmatic hernia
Congenital diseases
Coronary artery disease
Desaturation
extracorporeal oxygenation
Heart diseases
Heart rate
Hernia
Hernias
Mortality
Oxygenation
Pediatrics
persistent pulmonary hypertension of the neonate
Prenatal development
pulmonary hypoplasia
Septum
Transposition
transposition of the great arteries and intact ventricular septum
Ventricle
title Management of congenital diaphragmatic hernia with transposition of the great arteries
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