Under-recognised co-morbidities in idiopathic pulmonary fibrosis: A review
Co‐morbidities in idiopathic pulmonary fibrosis are common. These co‐morbidities include obstructive sleep apnoea, gastro‐oesophageal reflux disease, pulmonary hypertension and depression. The presence of co‐morbidities among patients with idiopathic pulmonary fibrosis contributes to worse quality o...
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Veröffentlicht in: | Respirology (Carlton, Vic.) Vic.), 2016-08, Vol.21 (6), p.995-1004 |
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description | Co‐morbidities in idiopathic pulmonary fibrosis are common. These co‐morbidities include obstructive sleep apnoea, gastro‐oesophageal reflux disease, pulmonary hypertension and depression. The presence of co‐morbidities among patients with idiopathic pulmonary fibrosis contributes to worse quality of life, morbidity and mortality. Despite the high prevalence of certain co‐morbidities in idiopathic pulmonary fibrosis, the optimal screening and management of many of these conditions remains unclear. The impact of co‐morbidities on this patient population is becoming more apparent. Their relevance will only increase as significant effort is being made to develop novel therapeutics that will alter the disease trajectory of patients with idiopathic pulmonary fibrosis. The purpose of this review is to focus on the epidemiology, pathophysiology, diagnosis and management of select co‐morbidities, including obstructive sleep apnoea, gastro‐oesophageal reflux disease, pulmonary hypertension and depression, in idiopathic pulmonary fibrosis. |
doi_str_mv | 10.1111/resp.12622 |
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These co‐morbidities include obstructive sleep apnoea, gastro‐oesophageal reflux disease, pulmonary hypertension and depression. The presence of co‐morbidities among patients with idiopathic pulmonary fibrosis contributes to worse quality of life, morbidity and mortality. Despite the high prevalence of certain co‐morbidities in idiopathic pulmonary fibrosis, the optimal screening and management of many of these conditions remains unclear. The impact of co‐morbidities on this patient population is becoming more apparent. Their relevance will only increase as significant effort is being made to develop novel therapeutics that will alter the disease trajectory of patients with idiopathic pulmonary fibrosis. 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These co‐morbidities include obstructive sleep apnoea, gastro‐oesophageal reflux disease, pulmonary hypertension and depression. The presence of co‐morbidities among patients with idiopathic pulmonary fibrosis contributes to worse quality of life, morbidity and mortality. Despite the high prevalence of certain co‐morbidities in idiopathic pulmonary fibrosis, the optimal screening and management of many of these conditions remains unclear. The impact of co‐morbidities on this patient population is becoming more apparent. Their relevance will only increase as significant effort is being made to develop novel therapeutics that will alter the disease trajectory of patients with idiopathic pulmonary fibrosis. The purpose of this review is to focus on the epidemiology, pathophysiology, diagnosis and management of select co‐morbidities, including obstructive sleep apnoea, gastro‐oesophageal reflux disease, pulmonary hypertension and depression, in idiopathic pulmonary fibrosis.</description><subject>Comorbidity</subject><subject>depression</subject><subject>Depression - epidemiology</subject><subject>Disease Management</subject><subject>gastro-oesophageal reflux disease</subject><subject>Gastroesophageal Reflux - epidemiology</subject><subject>Humans</subject><subject>Hypertension, Pulmonary - epidemiology</subject><subject>idiopathic pulmonary fibrosis</subject><subject>Idiopathic Pulmonary Fibrosis - diagnosis</subject><subject>Idiopathic Pulmonary Fibrosis - epidemiology</subject><subject>Idiopathic Pulmonary Fibrosis - physiopathology</subject><subject>Idiopathic Pulmonary Fibrosis - therapy</subject><subject>obstructive sleep apnoea</subject><subject>Prevalence</subject><subject>pulmonary hypertension</subject><subject>Sleep Apnea, Obstructive - epidemiology</subject><issn>1323-7799</issn><issn>1440-1843</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMtOwzAQRS0EglLY8AEoS4QU8DsJuwoBBSpAPMTSip0JGPLCbin9e1xaukTMZmZx7pHmIrRH8BEJc-zAd0eESkrXUI9wjmOScrYebkZZnCRZtoW2vX_DGDOBxSbaopJJQQXpoaunpgAXOzDtS2M9FJFp47p12hZ2bMFHtonC2Xb5-NWaqJtUddvkbhaVVrvWW38SDSIHnxamO2ijzCsPu8vdR0_nZ4-nw3h0e3F5OhjFRmBJ46KUjGmaUs0NBw4Fh8wkpdGGmgISZgrOMw1E5hrnsuQURJbmUiYp14KJjPXRwcLbufZjAn6sausNVFXeQDvxiqQ4lRxLLP-D8lSKIA3o4QI14S3voFSds3X4VBGs5jWrec3qp-YA7y-9E11DsUJ_ew0AWQBTW8HsD5W6P3u4-5XGi4z1Y_haZXL3rmTCEqGeby7U8PGcY3GN1TX7BmpVlw0</recordid><startdate>201608</startdate><enddate>201608</enddate><creator>de Boer, Kaïssa</creator><creator>Lee, Joyce S.</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7T5</scope><scope>H94</scope></search><sort><creationdate>201608</creationdate><title>Under-recognised co-morbidities in idiopathic pulmonary fibrosis: A review</title><author>de Boer, Kaïssa ; Lee, Joyce S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5062-df633b282b4c4e4ed4e9c7fcbc2cde73cd449be16ab0a6f42e598a66784b53593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Comorbidity</topic><topic>depression</topic><topic>Depression - epidemiology</topic><topic>Disease Management</topic><topic>gastro-oesophageal reflux disease</topic><topic>Gastroesophageal Reflux - epidemiology</topic><topic>Humans</topic><topic>Hypertension, Pulmonary - epidemiology</topic><topic>idiopathic pulmonary fibrosis</topic><topic>Idiopathic Pulmonary Fibrosis - diagnosis</topic><topic>Idiopathic Pulmonary Fibrosis - epidemiology</topic><topic>Idiopathic Pulmonary Fibrosis - physiopathology</topic><topic>Idiopathic Pulmonary Fibrosis - therapy</topic><topic>obstructive sleep apnoea</topic><topic>Prevalence</topic><topic>pulmonary hypertension</topic><topic>Sleep Apnea, Obstructive - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>de Boer, Kaïssa</creatorcontrib><creatorcontrib>Lee, Joyce S.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Respirology (Carlton, Vic.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>de Boer, Kaïssa</au><au>Lee, Joyce S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Under-recognised co-morbidities in idiopathic pulmonary fibrosis: A review</atitle><jtitle>Respirology (Carlton, Vic.)</jtitle><addtitle>Respirology</addtitle><date>2016-08</date><risdate>2016</risdate><volume>21</volume><issue>6</issue><spage>995</spage><epage>1004</epage><pages>995-1004</pages><issn>1323-7799</issn><eissn>1440-1843</eissn><abstract>Co‐morbidities in idiopathic pulmonary fibrosis are common. These co‐morbidities include obstructive sleep apnoea, gastro‐oesophageal reflux disease, pulmonary hypertension and depression. The presence of co‐morbidities among patients with idiopathic pulmonary fibrosis contributes to worse quality of life, morbidity and mortality. Despite the high prevalence of certain co‐morbidities in idiopathic pulmonary fibrosis, the optimal screening and management of many of these conditions remains unclear. The impact of co‐morbidities on this patient population is becoming more apparent. Their relevance will only increase as significant effort is being made to develop novel therapeutics that will alter the disease trajectory of patients with idiopathic pulmonary fibrosis. The purpose of this review is to focus on the epidemiology, pathophysiology, diagnosis and management of select co‐morbidities, including obstructive sleep apnoea, gastro‐oesophageal reflux disease, pulmonary hypertension and depression, in idiopathic pulmonary fibrosis.</abstract><cop>Australia</cop><pub>Blackwell Publishing Ltd</pub><pmid>26365251</pmid><doi>10.1111/resp.12622</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Comorbidity depression Depression - epidemiology Disease Management gastro-oesophageal reflux disease Gastroesophageal Reflux - epidemiology Humans Hypertension, Pulmonary - epidemiology idiopathic pulmonary fibrosis Idiopathic Pulmonary Fibrosis - diagnosis Idiopathic Pulmonary Fibrosis - epidemiology Idiopathic Pulmonary Fibrosis - physiopathology Idiopathic Pulmonary Fibrosis - therapy obstructive sleep apnoea Prevalence pulmonary hypertension Sleep Apnea, Obstructive - epidemiology |
title | Under-recognised co-morbidities in idiopathic pulmonary fibrosis: A review |
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