Severe Radiation Necrosis Successfully Treated With Bevacizumab in an Infant with Low-Grade Glioma and Tumor-Associated Intractable Trigeminal Neuralgia

We present a unique case of radiation necrosis in a child with brain stem low‐grade glioma (LGG) presenting with trigeminal neuralgia. Despite extensive therapies, severe pain persisted. She received proton beam radiation with significant improvement. However, she developed radiation necrosis and hy...

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Veröffentlicht in:	Pediatric blood & cancer 2016-09, Vol.63 (9), p.1671-1673
Hauptverfasser:	Pillay Smiley, Natasha, Alden, Tord, Hartsell, William, Fangusaro, Jason
Format:	Artikel
Sprache:	eng
Schlagworte:	Bevacizumab - therapeutic use Brain Neoplasms - complications Brain Neoplasms - radiotherapy facial tics Female Gangrene Glioma - complications Glioma - radiotherapy Hematology Humans Hydrocephalus - etiology Infant infant low-grade glioma Necrosis Oncology pain Pediatrics pilomyxoid astrocytoma proton beam radiation Proton Therapy - adverse effects Radiation Injuries - drug therapy Trigeminal Neuralgia - radiotherapy
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