Apoptosis in cryopreserved eukaryotic cells

This review considers apoptosis mechanisms that have been revealed in cryopreserved cells and which can be controlled using different chemical agents, thereby improving the viability of cells after their return to normal conditions. The role of oxidative stress as of the most significant damaging fa...

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Veröffentlicht in:Biochemistry (Moscow) 2016-05, Vol.81 (5), p.445-452
Hauptverfasser: Savitskaya, M. A., Onishchenko, G. E.
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Onishchenko, G. E.
description This review considers apoptosis mechanisms that have been revealed in cryopreserved cells and which can be controlled using different chemical agents, thereby improving the viability of cells after their return to normal conditions. The role of oxidative stress as of the most significant damaging factor is discussed, as well as the reasonability of including antioxidants into cryopreservation/thawing protocols as independent agents or in combination with other compounds.
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subjects Antioxidants
Apoptosis
Autophagy
Biochemistry
Biomedical and Life Sciences
Biomedicine
Bioorganic Chemistry
Caspases - metabolism
Cellular biology
Chemical agents
Cryopreservation
DNA Damage
Eukaryotic Cells - cytology
Eukaryotic Cells - metabolism
Humans
Life Sciences
Microbiology
Oxidative Stress
Receptors, Death Domain - metabolism
Reviews
Thawing
title Apoptosis in cryopreserved eukaryotic cells
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