Phage-displayed macrocyclic glycopeptide libraries

In this report, we describe an efficient way to generate libraries of macrocyclic glycopeptides in one step by reacting phage-displayed libraries of peptides with dichloro-oxime derivatives. We showed that the reactions do not interfere with the ability of phage to replicate in bacteria. The reactio...

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Veröffentlicht in:	Organic & biomolecular chemistry 2016-01, Vol.14 (24), p.5539-5545
Hauptverfasser:	Ng, Simon, Derda, Ratmir
Format:	Artikel
Sprache:	eng
Schlagworte:	Glycopeptides - chemistry Macrocyclic Compounds - chemistry Peptide Library
Online-Zugang:	Volltext
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