Effects of sodium fluoride on immune response in murine macrophages

Excessive fluoride intake may be harmful for health, producing dental and skeletal fluorosis, and effects upon neurobehavioral development. Studies in animals have revealed effects upon the gastrointestinal, renal and reproductive systems. Some of the disorders may be a consequence of immune system...

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Veröffentlicht in:	Toxicology in vitro 2016-08, Vol.34, p.81-87
Hauptverfasser:	De la Fuente, Beatriz, Vázquez, Marta, Rocha, René Antonio, Devesa, Vicenta, Vélez, Dinoraz
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cytokines Fluoride Immunotoxicity Lipid Peroxidation - drug effects Lipopolysaccharides Macrophages Macrophages - drug effects Macrophages - metabolism Macrophages - physiology Mice Mitochondria - drug effects Mitochondria - metabolism Oxidative stress Phagocytosis Phagocytosis - drug effects RAW 264.7 Cells Reactive Nitrogen Species - metabolism Reactive Oxygen Species - metabolism Sodium Fluoride - toxicity
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