Evaluation of a transcription mediated amplification assay for detection of herpes simplex virus types 1 and 2 mRNA in clinical specimens

Highlights • Herpes simplex viruses (HSVs) are double-stranded DNA viruses that package viral mRNAs. • A real time amplified molecular test was designed to detect packaged viral mRNA. • This test exhibited high clinical sensitivity and specificity in an STD clinic population.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of clinical virology 2016-07, Vol.80, p.62-67
Hauptverfasser:	Swenson, Paul D, El-Sabaeny, Azza, Thomas-Moricz, Vanessa, Allen, Megan, Groskopf, Anabel, Jiang, Alice, Getman, Damon
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Aptima Cytomegalovirus Female Herpes Simplex - diagnosis Herpes simplex virus (HSV) Herpes simplex virus 1 Herpes simplex virus 2 Herpesvirus 1, Human - genetics Herpesvirus 1, Human - growth & development Herpesvirus 2, Human - genetics Herpesvirus 2, Human - growth & development Human herpesvirus 3 Human herpesvirus 4 Human herpesvirus 5 Human herpesvirus 6 Human herpesvirus 8 Humans Infectious Disease Male Real-Time Polymerase Chain Reaction RNA, Messenger - analysis RNA, Viral - analysis Sensitivity and Specificity Transcription, Genetic Transcription-mediated amplification UL42 mRNA
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • Herpes simplex viruses (HSVs) are double-stranded DNA viruses that package viral mRNAs. • A real time amplified molecular test was designed to detect packaged viral mRNA. • This test exhibited high clinical sensitivity and specificity in an STD clinic population.
ISSN:	1386-6532 1873-5967
DOI:	10.1016/j.jcv.2016.04.023