Detergent sclerosants at sub-lytic concentrations induce endothelial cell apoptosis through a caspase dependent pathway

To investigate the apoptotic effects of detergent sclerosants sodium tetradecylsulphate (STS) and polidocanol (POL) on endothelial cells at sub-lytic concentrations. Human umbilical vein endothelial cells (HUVECs) were isolated and labelled with antibodies to assess for apoptosis and examined with c...

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Veröffentlicht in:	Apoptosis (London) 2016-07, Vol.21 (7), p.836-845
Hauptverfasser:	Cooley-Andrade, Osvaldo, Cheung, Kelvin, Chew, An-Ning, Connor, David Ewan, Parsi, Kurosh
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Apoptosis Apoptosis - drug effects Biochemistry Biomedical and Life Sciences Biomedicine Borates - pharmacology Cancer Research Caspase 3 - genetics Caspase 3 - metabolism Caspase 8 - genetics Caspase 8 - metabolism Caspase 9 - genetics Caspase 9 - metabolism Cell Biology Cells, Cultured Detergents - pharmacology Detergents, Synthetic Endothelium Ethylenediaminetetraacetic acid Human Umbilical Vein Endothelial Cells - cytology Human Umbilical Vein Endothelial Cells - drug effects Human Umbilical Vein Endothelial Cells - enzymology Humans Iodides Oncology Polyethylene Glycols - pharmacology Sclerosing Solutions - pharmacology Signal Transduction Viral antibodies Virology
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