Investigation of serum levels and tissue expression of two genes IGFBP-2 and IGFBP-3 act as potential biomarker for predicting the progression and survival in patients with glioblastoma multiforme

Abstract Background Identification of genetic copy number changes in glial tumors is of importance in the context of improved/refined diagnostic, prognostic procedures and therapeutic decision-making. Blood-derived biomarkers, therefore, would be useful as minimally invasive markers that could suppo...

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Veröffentlicht in:	Journal of the neurological sciences 2016-07, Vol.366, p.202-206
Hauptverfasser:	Abdolhoseinpour, Hesam, Mehrabi, Farzad, Shahraki, Kourosh, Khoshnood, Reza Jalili, Masoumi, Babak, Yahaghi, Emad, Goudarzi, Peyman Karimi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Aging - metabolism Analysis Biomarkers, Tumor - metabolism Blood Chemical Analysis Brain - metabolism Brain - pathology Brain Neoplasms - metabolism Brain Neoplasms - pathology ELISA Enzyme-Linked Immunosorbent Assay Female Gene Glioblastoma - metabolism Glioblastoma - pathology Glioblastoma multiforme Humans IGFBP-2 and IGFBP-3 Immunohistochemistry Insulin-Like Growth Factor Binding Protein 2 - metabolism Insulin-Like Growth Factor Binding Protein 3 - metabolism Kaplan-Meier Estimate Male Middle Aged Neurology Plasma Sex Characteristics Tumor Burden
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