Triclosan (TCS) and Triclocarban (TCC) cause lifespan reduction and reproductive impairment through oxidative stress-mediated expression of the defensome in the monogonont rotifer (Brachionus koreanus)

Triclosan (TCS) and Triclocarban (TCC) are used as antimicrobial agents and have been widely dispersed and detected in the marine environment. However, the toxicities of TCS and TCC have been poorly investigated in marine invertebrates. In this study, the effects of TCS and TCC on mortality, populat...

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Veröffentlicht in:	Comparative biochemistry and physiology. Toxicology & pharmacology 2016-07, Vol.185-186, p.131-137
Hauptverfasser:	Han, Jeonghoon, Won, Eun-Ji, Hwang, Un-Ki, Kim, Il-Chan, Yim, Joung Han, Lee, Jae-Seong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - metabolism Brachionus Brachionus koreanus Carbanilides - toxicity Cytochrome P-450 Enzyme System - genetics Cytochrome P-450 Enzyme System - metabolism Dose-Response Relationship, Drug Fertility - drug effects Gene Expression Regulation Glutathione Transferase - genetics Glutathione Transferase - metabolism Heat-Shock Proteins - genetics Heat-Shock Proteins - metabolism Helminth Proteins - genetics Helminth Proteins - metabolism Lethal Dose 50 Longevity - drug effects Oxidative Stress - drug effects Reactive oxygen species Reactive Oxygen Species - metabolism Reproduction - drug effects Rotifer Rotifera Rotifera - drug effects Rotifera - genetics Rotifera - growth & development Rotifera - metabolism Time Factors Triclocarban (TCC) Triclosan (TCS) Triclosan - toxicity Water Pollutants, Chemical - toxicity
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