Synthesis of 2-diphospho-myo-inositol 1,3,4,5,6-pentakisphosphate and a photocaged analogue

Diphosphoinositol polyphosphates (inositol pyrophosphates, X-InsP7) are a family of second messengers with important roles in eukaryotic biology. Their chemical synthesis and modification remains a challenging task due to the high density of phosphate groups arranged around the myo-inositol core. He...

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Veröffentlicht in:Organic & biomolecular chemistry 2016-01, Vol.14 (24), p.5559-5562
Hauptverfasser: Pavlovic, I, Thakor, D T, Jessen, H J
Format: Artikel
Sprache:eng
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