A8.17Effective use of bortezomib and plasma filtration in a critically ill patient with lupus nephritis and myocarditis: a case report and dynamics of (immuno) proteasome inhibition

Background and objectives(Immuno) proteasomes play a crucial role in processing of key proteins involved in the functioning of immune effector cells implicated in the pathology of autoimmune diseases. To this end, proteasome inhibitors, e.g. bortezomib, have received considerable attention as experi...

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Veröffentlicht in:Annals of the rheumatic diseases 2015-03, Vol.74 (Suppl 1), p.A88-A88
Hauptverfasser: Tsang-A-Sjoe, MWP, de Groot, KA, Niewerth, D, Cloos, J, Blank, J L, Zweegman, S, Jansen, G, Voskuyl, A E, van der Heijden, JW
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Sprache:eng
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