Self-assembled triangular DNA nanoparticles are an efficient system for gene delivery

Developing an advanced nucleic acid drug delivery system is of great significance in order to achieve optimal gene delivery. Self-assembled nucleic acid nanoparticles are an excellent platform for the delivery of nucleic acids and other small molecular drugs. In this study, we developed the efficien...

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Veröffentlicht in:	Journal of controlled release 2016-07, Vol.233, p.126-135
Hauptverfasser:	Wang, Yingming, You, Zaichun, Du, Juan, Li, Hongli, Chen, Huaping, Li, Jingtong, Dong, Weijie, He, Binfeng, Mao, Chengde, Wang, Guansong
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor DNA - administration & dosage DNA nanostructures Endocytosis Gene delivery Gene Transfer Techniques Humans Nanoparticles - administration & dosage RNA, Messenger - metabolism RNA, Small Interfering - administration & dosage Self-assembled Single-stranded siRNA TOR Serine-Threonine Kinases - genetics TOR Serine-Threonine Kinases - metabolism
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