ED-36 INHERITED VARIANTS NEAR TERC AND TERT ARE ASSOCIATED WITH LONGER TELOMERES AND INCREASED GLIOMA RISK: GENOME-WIDE ASSOCIATION RESULTS FROM THE UCSF ADULT GLIOMA STUDY AND THE ENGAGE CONSORTIUM TELOMERE GROUP

High-grade glioma, the most common central nervous system cancer in adults, has poor prognosis. We performed a genome-wide association study (GWAS) and replication analysis of high-grade glioma risk (N = 1,644 cases and 7,736 controls). We identify a novel inherited glioma risk locus, rs1920116 (nea...

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2014-11, Vol.16 (suppl 5), p.v73-v74
Hauptverfasser:	Walsh, K., Codd, V., Smirnov, I., Rice, T., Decker, P., Hansen, H., Molinaro, A., Pekmezci, M., Tihan, T., Berger, M., Chang, S., Prados, M., Lachance, D., O'Neill, B. P., van der Harst, P., Wiencke, J., Samani, N., Jenkins, R., Wrensch, M.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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