An antibody reactive to the Gly sub(63)-Lys sub(68) epitope of NT-proBNP exhibits O-glycosylation-independent binding

The N-terminal fragment of prohormone brain natriuretic peptide (NT-proBNP) is a commonly used biomarker for the diagnosis of congestive heart failure, although its biological function is not well known. NT-proBNP exhibits heavy O-linked glycosylation, and it is quite difficult to develop an antibod...

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Veröffentlicht in:Experimental & molecular medicine 2014-09, Vol.46 (9), p.e114-e114
Hauptverfasser: Lee, Yujean, Kim, Hyori, Chung, Junho
Format: Artikel
Sprache:eng
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