Therapeutic inhibition of breast cancer bone metastasis progression and lung colonization: breaking the vicious cycle by targeting alpha 5 beta 1 integrin

At diagnosis, 10 % of breast cancer patients already have locally advanced or metastatic disease; moreover, metastasis eventually develops in at least 40 % of early breast cancer patients. Osteolytic bone colonization occurs in 80-85 % of metastatic breast cancer patients and is thought to be an ear...

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Veröffentlicht in:	Breast cancer research and treatment 2016-06, Vol.157 (3), p.489-501
Hauptverfasser:	Yao, Hongren, Veine, Donna M, Livant, Donna L
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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