TMEPAI increases lysosome stability and promotes autophagy

Autophagy is emerging as a critical response of normal and cancer cells to environmental changes and plays an important role in cell metabolism and maintenance of damaged organelles. Transmembrane prostate androgen-induced protein (TMEPAI) is a pro-tumorigenic factor with high expression in tumor ce...

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Veröffentlicht in:	The international journal of biochemistry & cell biology 2016-07, Vol.76, p.98-106
Hauptverfasser:	Luo, Shenheng, Yang, Meng, Lv, Dan, Jing, Lei, Li, Yuyin, Liu, Zhenxing, Diao, Aipo
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Autophagy Beclin-1 Beclin-1 - biosynthesis Beclin-1 - genetics Cancer cell Female Gene Expression Regulation, Neoplastic Humans Lysosome Lysosomes - genetics Lysosomes - metabolism Lysosomes - pathology Male MCF-7 Cells Membrane Proteins - genetics Membrane Proteins - metabolism Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Neoplasms - genetics Neoplasms - metabolism Neoplasms - pathology TMEPAI
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