Cardiac index after acute ST-segment elevation myocardial infarction measured with phase-contrast cardiac magnetic resonance imaging

Objectives Phase-contrast CMR (PC-CMR) might provide a fast and robust non-invasive determination of left ventricular function in patients after ST-segment elevation myocardial infarction (STEMI). Methods Cine sequences in the left-ventricular (LV) short-axis and free-breathing, retrospectively gate...

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Veröffentlicht in:European radiology 2016-07, Vol.26 (7), p.1999-2008
Hauptverfasser: Klug, Gert, Reinstadler, Sebastian Johannes, Feistritzer, Hans-Josef, Kremser, Christian, Schwaiger, Johannes P., Reindl, Martin, Mair, Johannes, Müller, Silvana, Mayr, Agnes, Franz, Wolfgang-Michael, Metzler, Bernhard
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container_end_page 2008
container_issue 7
container_start_page 1999
container_title European radiology
container_volume 26
creator Klug, Gert
Reinstadler, Sebastian Johannes
Feistritzer, Hans-Josef
Kremser, Christian
Schwaiger, Johannes P.
Reindl, Martin
Mair, Johannes
Müller, Silvana
Mayr, Agnes
Franz, Wolfgang-Michael
Metzler, Bernhard
description Objectives Phase-contrast CMR (PC-CMR) might provide a fast and robust non-invasive determination of left ventricular function in patients after ST-segment elevation myocardial infarction (STEMI). Methods Cine sequences in the left-ventricular (LV) short-axis and free-breathing, retrospectively gated PC-CMR were performed in 90 patients with first acute STEMI and 15 healthy volunteers. Inter- and intra-observer agreement was determined. The correlations of clinical variables (age, gender, ejection fraction, NT pro-brain natriuretic peptide [NT-proBNP] with cardiac index (CI) were calculated. Results For CI, there was a strong agreement of cine CMR with PC-CMR in healthy volunteers (r: 0.82, mean difference: -0.14 l/min/m 2 , error ± 23 %). Agreement was lower in STEMI patients (r: 0.61, mean difference: -0.17 l/min/m 2 , error ± 32 %). In STEMI patients, CI measured with PC-CMR showed lower intra-observer (1 % vs. 9 %) and similar inter-observer variability (9 % vs. 12 %) compared to cine CMR. CI was significantly correlated with age, ejection fraction and NT-proBNP values in STEMI patients. Discussion The agreement of PC-CMR and cine CMR for the determination of CI is lower in STEMI patients than in healthy volunteers. After acute STEMI, CI measured with PC-CMR decreases with age, LV ejection fraction and higher NT-proBNP. Key Points • Cine CMR and PC-CMR correlate well in healthy volunteers . • Agreement is lower in STEMI patients . • Cardiac Output should be measured with one method longitudinally . • Cardiac output decreases with age after myocardial infarction .
doi_str_mv 10.1007/s00330-015-4022-7
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Key Points • Cine CMR and PC-CMR correlate well in healthy volunteers . • Agreement is lower in STEMI patients . • Cardiac Output should be measured with one method longitudinally . • Cardiac output decreases with age after myocardial infarction .</description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-015-4022-7</identifier><identifier>PMID: 26385805</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Aged ; Agreements ; Angioplasty ; Aorta - physiopathology ; Blood Flow Velocity - physiology ; Cardiac Output - physiology ; Contrast Media - administration &amp; dosage ; Coronary Circulation - physiology ; Diagnostic Radiology ; Ejection fraction ; Female ; Follow-Up Studies ; Heart attacks ; Heart Rate - physiology ; Hemodynamics ; Humans ; Image Interpretation, Computer-Assisted - methods ; Imaging ; Internal Medicine ; Interventional Radiology ; Magnetic Resonance ; Magnetic Resonance Imaging ; Magnetic Resonance Imaging, Cine - methods ; Male ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Neuroradiology ; Patients ; Peptides ; Prospective Studies ; Radiology ; ST Elevation Myocardial Infarction - pathology ; ST Elevation Myocardial Infarction - physiopathology ; Ultrasound ; Ventricular Function, Left - physiology</subject><ispartof>European radiology, 2016-07, Vol.26 (7), p.1999-2008</ispartof><rights>European Society of Radiology 2015</rights><rights>European Society of Radiology 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c405t-8e3c91cc3da41084e5c3db55b1c29a6af17063081041860972a4f712325176723</citedby><cites>FETCH-LOGICAL-c405t-8e3c91cc3da41084e5c3db55b1c29a6af17063081041860972a4f712325176723</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00330-015-4022-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00330-015-4022-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26385805$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Klug, Gert</creatorcontrib><creatorcontrib>Reinstadler, Sebastian Johannes</creatorcontrib><creatorcontrib>Feistritzer, Hans-Josef</creatorcontrib><creatorcontrib>Kremser, Christian</creatorcontrib><creatorcontrib>Schwaiger, Johannes P.</creatorcontrib><creatorcontrib>Reindl, Martin</creatorcontrib><creatorcontrib>Mair, Johannes</creatorcontrib><creatorcontrib>Müller, Silvana</creatorcontrib><creatorcontrib>Mayr, Agnes</creatorcontrib><creatorcontrib>Franz, Wolfgang-Michael</creatorcontrib><creatorcontrib>Metzler, Bernhard</creatorcontrib><title>Cardiac index after acute ST-segment elevation myocardial infarction measured with phase-contrast cardiac magnetic resonance imaging</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><addtitle>Eur Radiol</addtitle><description>Objectives Phase-contrast CMR (PC-CMR) might provide a fast and robust non-invasive determination of left ventricular function in patients after ST-segment elevation myocardial infarction (STEMI). Methods Cine sequences in the left-ventricular (LV) short-axis and free-breathing, retrospectively gated PC-CMR were performed in 90 patients with first acute STEMI and 15 healthy volunteers. Inter- and intra-observer agreement was determined. The correlations of clinical variables (age, gender, ejection fraction, NT pro-brain natriuretic peptide [NT-proBNP] with cardiac index (CI) were calculated. Results For CI, there was a strong agreement of cine CMR with PC-CMR in healthy volunteers (r: 0.82, mean difference: -0.14 l/min/m 2 , error ± 23 %). Agreement was lower in STEMI patients (r: 0.61, mean difference: -0.17 l/min/m 2 , error ± 32 %). In STEMI patients, CI measured with PC-CMR showed lower intra-observer (1 % vs. 9 %) and similar inter-observer variability (9 % vs. 12 %) compared to cine CMR. CI was significantly correlated with age, ejection fraction and NT-proBNP values in STEMI patients. Discussion The agreement of PC-CMR and cine CMR for the determination of CI is lower in STEMI patients than in healthy volunteers. After acute STEMI, CI measured with PC-CMR decreases with age, LV ejection fraction and higher NT-proBNP. 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Methods Cine sequences in the left-ventricular (LV) short-axis and free-breathing, retrospectively gated PC-CMR were performed in 90 patients with first acute STEMI and 15 healthy volunteers. Inter- and intra-observer agreement was determined. The correlations of clinical variables (age, gender, ejection fraction, NT pro-brain natriuretic peptide [NT-proBNP] with cardiac index (CI) were calculated. Results For CI, there was a strong agreement of cine CMR with PC-CMR in healthy volunteers (r: 0.82, mean difference: -0.14 l/min/m 2 , error ± 23 %). Agreement was lower in STEMI patients (r: 0.61, mean difference: -0.17 l/min/m 2 , error ± 32 %). In STEMI patients, CI measured with PC-CMR showed lower intra-observer (1 % vs. 9 %) and similar inter-observer variability (9 % vs. 12 %) compared to cine CMR. CI was significantly correlated with age, ejection fraction and NT-proBNP values in STEMI patients. Discussion The agreement of PC-CMR and cine CMR for the determination of CI is lower in STEMI patients than in healthy volunteers. After acute STEMI, CI measured with PC-CMR decreases with age, LV ejection fraction and higher NT-proBNP. Key Points • Cine CMR and PC-CMR correlate well in healthy volunteers . • Agreement is lower in STEMI patients . • Cardiac Output should be measured with one method longitudinally . • Cardiac output decreases with age after myocardial infarction .</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>26385805</pmid><doi>10.1007/s00330-015-4022-7</doi><tpages>10</tpages></addata></record>
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subjects Adult
Aged
Agreements
Angioplasty
Aorta - physiopathology
Blood Flow Velocity - physiology
Cardiac Output - physiology
Contrast Media - administration & dosage
Coronary Circulation - physiology
Diagnostic Radiology
Ejection fraction
Female
Follow-Up Studies
Heart attacks
Heart Rate - physiology
Hemodynamics
Humans
Image Interpretation, Computer-Assisted - methods
Imaging
Internal Medicine
Interventional Radiology
Magnetic Resonance
Magnetic Resonance Imaging
Magnetic Resonance Imaging, Cine - methods
Male
Medicine
Medicine & Public Health
Middle Aged
Neuroradiology
Patients
Peptides
Prospective Studies
Radiology
ST Elevation Myocardial Infarction - pathology
ST Elevation Myocardial Infarction - physiopathology
Ultrasound
Ventricular Function, Left - physiology
title Cardiac index after acute ST-segment elevation myocardial infarction measured with phase-contrast cardiac magnetic resonance imaging
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