Clearance of donor cell leukemia by means of graft versus leukemia effect: A case report
Donor cell leukemia (DCL) is a rare complication of hematopoietic stem cell transplantation (HSCT). Its incidence has been reported between 0.12 and 5%, although the majority of cases are anecdotal. The mechanisms of leukemogenesis in DCL may be distinct from other types of leukemia. Here we describ...
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| Veröffentlicht in: | Hematology (Luxembourg) 2016-09, Vol.21 (8), p.470-473 |
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| container_title | Hematology (Luxembourg) |
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| creator | Ruiz-Delgado, Guillermo J León Peña, Andrés A Gómez-de-León, Andrés Ruiz-Argüelles, Guillermo J |
| description | Donor cell leukemia (DCL) is a rare complication of hematopoietic stem cell transplantation (HSCT). Its incidence has been reported between 0.12 and 5%, although the majority of cases are anecdotal. The mechanisms of leukemogenesis in DCL may be distinct from other types of leukemia. Here we describe a case of a 27-year-old woman with a diagnosis of biphenotypic acute leukemia who received a HSCT and developed a DCL. We briefly discuss the possible pathogenesis, diagnosis, and treatment of DCL. |
| doi_str_mv | 10.1080/10245332.2015.1117741 |
| format | Article |
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| source | MEDLINE; EZB Electronic Journals Library |
| subjects | Adult Female Graft vs Host Disease - etiology Hematopoietic Stem Cell Transplantation - adverse effects Humans Leukemia - complications Tissue Donors |
| title | Clearance of donor cell leukemia by means of graft versus leukemia effect: A case report |
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