Efficient, rapid and one pot synthesis of 2-substituted benzimidazoles using the NaOH/I sub(2) system as an oxidant under mild conditions

A one-pot efficient synthesis of benzimidazole derivatives has been achieved from aryl aldehydes and o-phenylenediamine in the presence of the NaOH/I2 system at room temperature in acetonitrile. The simplicity of the procedure and work-up, larger scale synthesis, high yields and short reaction times...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of chemical research 2013-04, Vol.37 (4)
Hauptverfasser:	Naeimi, Hossein, Alishahi, Nasrin
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetonitrile Aromatic compounds Derivatives Oxidants Oxidizing agents Reaction time Synthesis Synthesis (chemistry)
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page
container_issue	4
container_start_page
container_title	Journal of chemical research
container_volume	37
creator	Naeimi, Hossein Alishahi, Nasrin
description	A one-pot efficient synthesis of benzimidazole derivatives has been achieved from aryl aldehydes and o-phenylenediamine in the presence of the NaOH/I2 system at room temperature in acetonitrile. The simplicity of the procedure and work-up, larger scale synthesis, high yields and short reaction times are the advantages of this method.
doi_str_mv	10.3184/174751913X13636014702351
format	Article
fullrecord	<record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_miscellaneous_1808118492</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1808118492</sourcerecordid><originalsourceid>FETCH-proquest_miscellaneous_18081184923</originalsourceid><addsrcrecordid>eNqV0LtOxDAQhWELgUS4vMOUi0RYO861Rot2G2go6FbeeAKDEjtkbAn2DXhrjMQLUJ3m018cIUDJO63acq2asqlUp_SL0rWupSobWehKnYiskGWT15VsTkX2y_Lk2nNxwfwuZVnVncrE92YYqCd04RYWM5MF4yx4hzD7APzlwhsyMfgBipzjgQOFGNDCAd2RJrLm6EdkiEzuFRKGR_O0Xe8g2VVxkwoccALDqQv-M3kXIDqLC0w0Wui9sxTIO74SZ4MZGa__9lKsHjbP99t8XvxHRA77ibjHcTQOfeS9amWr0gNdof9BfwBXh19O</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1808118492</pqid></control><display><type>article</type><title>Efficient, rapid and one pot synthesis of 2-substituted benzimidazoles using the NaOH/I sub(2) system as an oxidant under mild conditions</title><source>Sage Journals GOLD Open Access 2024</source><source>Alma/SFX Local Collection</source><creator>Naeimi, Hossein ; Alishahi, Nasrin</creator><creatorcontrib>Naeimi, Hossein ; Alishahi, Nasrin</creatorcontrib><description>A one-pot efficient synthesis of benzimidazole derivatives has been achieved from aryl aldehydes and o-phenylenediamine in the presence of the NaOH/I2 system at room temperature in acetonitrile. The simplicity of the procedure and work-up, larger scale synthesis, high yields and short reaction times are the advantages of this method.</description><identifier>ISSN: 1747-5198</identifier><identifier>EISSN: 2047-6507</identifier><identifier>DOI: 10.3184/174751913X13636014702351</identifier><language>eng</language><subject>Acetonitrile ; Aromatic compounds ; Derivatives ; Oxidants ; Oxidizing agents ; Reaction time ; Synthesis ; Synthesis (chemistry)</subject><ispartof>Journal of chemical research, 2013-04, Vol.37 (4)</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Naeimi, Hossein</creatorcontrib><creatorcontrib>Alishahi, Nasrin</creatorcontrib><title>Efficient, rapid and one pot synthesis of 2-substituted benzimidazoles using the NaOH/I sub(2) system as an oxidant under mild conditions</title><title>Journal of chemical research</title><description>A one-pot efficient synthesis of benzimidazole derivatives has been achieved from aryl aldehydes and o-phenylenediamine in the presence of the NaOH/I2 system at room temperature in acetonitrile. The simplicity of the procedure and work-up, larger scale synthesis, high yields and short reaction times are the advantages of this method.</description><subject>Acetonitrile</subject><subject>Aromatic compounds</subject><subject>Derivatives</subject><subject>Oxidants</subject><subject>Oxidizing agents</subject><subject>Reaction time</subject><subject>Synthesis</subject><subject>Synthesis (chemistry)</subject><issn>1747-5198</issn><issn>2047-6507</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNqV0LtOxDAQhWELgUS4vMOUi0RYO861Rot2G2go6FbeeAKDEjtkbAn2DXhrjMQLUJ3m018cIUDJO63acq2asqlUp_SL0rWupSobWehKnYiskGWT15VsTkX2y_Lk2nNxwfwuZVnVncrE92YYqCd04RYWM5MF4yx4hzD7APzlwhsyMfgBipzjgQOFGNDCAd2RJrLm6EdkiEzuFRKGR_O0Xe8g2VVxkwoccALDqQv-M3kXIDqLC0w0Wui9sxTIO74SZ4MZGa__9lKsHjbP99t8XvxHRA77ibjHcTQOfeS9amWr0gNdof9BfwBXh19O</recordid><startdate>20130401</startdate><enddate>20130401</enddate><creator>Naeimi, Hossein</creator><creator>Alishahi, Nasrin</creator><scope>7SR</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope></search><sort><creationdate>20130401</creationdate><title>Efficient, rapid and one pot synthesis of 2-substituted benzimidazoles using the NaOH/I sub(2) system as an oxidant under mild conditions</title><author>Naeimi, Hossein ; Alishahi, Nasrin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_18081184923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Acetonitrile</topic><topic>Aromatic compounds</topic><topic>Derivatives</topic><topic>Oxidants</topic><topic>Oxidizing agents</topic><topic>Reaction time</topic><topic>Synthesis</topic><topic>Synthesis (chemistry)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Naeimi, Hossein</creatorcontrib><creatorcontrib>Alishahi, Nasrin</creatorcontrib><collection>Engineered Materials Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><jtitle>Journal of chemical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Naeimi, Hossein</au><au>Alishahi, Nasrin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficient, rapid and one pot synthesis of 2-substituted benzimidazoles using the NaOH/I sub(2) system as an oxidant under mild conditions</atitle><jtitle>Journal of chemical research</jtitle><date>2013-04-01</date><risdate>2013</risdate><volume>37</volume><issue>4</issue><issn>1747-5198</issn><eissn>2047-6507</eissn><abstract>A one-pot efficient synthesis of benzimidazole derivatives has been achieved from aryl aldehydes and o-phenylenediamine in the presence of the NaOH/I2 system at room temperature in acetonitrile. The simplicity of the procedure and work-up, larger scale synthesis, high yields and short reaction times are the advantages of this method.</abstract><doi>10.3184/174751913X13636014702351</doi></addata></record>
fulltext	fulltext
identifier	ISSN: 1747-5198
ispartof	Journal of chemical research, 2013-04, Vol.37 (4)
issn	1747-5198 2047-6507
language	eng
recordid	cdi_proquest_miscellaneous_1808118492
source	Sage Journals GOLD Open Access 2024; Alma/SFX Local Collection
subjects	Acetonitrile Aromatic compounds Derivatives Oxidants Oxidizing agents Reaction time Synthesis Synthesis (chemistry)
title	Efficient, rapid and one pot synthesis of 2-substituted benzimidazoles using the NaOH/I sub(2) system as an oxidant under mild conditions
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T03%3A13%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Efficient,%20rapid%20and%20one%20pot%20synthesis%20of%202-substituted%20benzimidazoles%20using%20the%20NaOH/I%20sub(2)%20system%20as%20an%20oxidant%20under%20mild%20conditions&rft.jtitle=Journal%20of%20chemical%20research&rft.au=Naeimi,%20Hossein&rft.date=2013-04-01&rft.volume=37&rft.issue=4&rft.issn=1747-5198&rft.eissn=2047-6507&rft_id=info:doi/10.3184/174751913X13636014702351&rft_dat=%3Cproquest%3E1808118492%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1808118492&rft_id=info:pmid/&rfr_iscdi=true