Double-wire sternal closure technique in bovine animal models for total artificial heart implant
In vivo preclinical testing of mechanical circulatory devices requires large animal models that provide reliable physiological and hemodynamic conditions by which to test the device and investigate design and development strategies. Large bovine species are commonly used for mechanical circulatory s...
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Veröffentlicht in: | International journal of artificial organs 2015-08, Vol.38 (8), p.465-467 |
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container_title | International journal of artificial organs |
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creator | Karimov, Jamshid H Sunagawa, Gengo Golding, Leonard A R Moazami, Nader Fukamachi, Kiyotaka |
description | In vivo preclinical testing of mechanical circulatory devices requires large animal models that provide reliable physiological and hemodynamic conditions by which to test the device and investigate design and development strategies. Large bovine species are commonly used for mechanical circulatory support device research. The animals used for chronic in vivo support require high-quality care and excellent surgical techniques as well as advanced methods of postoperative care. These techniques are constantly being updated and new methods are emerging.We report results of our double steel-wire closure technique in large bovine models used for Cleveland Clinic's continuous-flow total artificial heart development program. This is the first report of double-wire sternal fixation used in large bovine models. |
doi_str_mv | 10.5301/ijao.5000426 |
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source | MEDLINE; SAGE Complete A-Z List |
subjects | Animals Artificial organs Cattle Circulation Devices Heart, Artificial In vivo methods and tests In vivo testing In vivo tests Models, Animal Sternotomy Sternum - surgery Surgical implants Suture Techniques |
title | Double-wire sternal closure technique in bovine animal models for total artificial heart implant |
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