Double-wire sternal closure technique in bovine animal models for total artificial heart implant

In vivo preclinical testing of mechanical circulatory devices requires large animal models that provide reliable physiological and hemodynamic conditions by which to test the device and investigate design and development strategies. Large bovine species are commonly used for mechanical circulatory s...

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Veröffentlicht in:International journal of artificial organs 2015-08, Vol.38 (8), p.465-467
Hauptverfasser: Karimov, Jamshid H, Sunagawa, Gengo, Golding, Leonard A R, Moazami, Nader, Fukamachi, Kiyotaka
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container_issue 8
container_start_page 465
container_title International journal of artificial organs
container_volume 38
creator Karimov, Jamshid H
Sunagawa, Gengo
Golding, Leonard A R
Moazami, Nader
Fukamachi, Kiyotaka
description In vivo preclinical testing of mechanical circulatory devices requires large animal models that provide reliable physiological and hemodynamic conditions by which to test the device and investigate design and development strategies. Large bovine species are commonly used for mechanical circulatory support device research. The animals used for chronic in vivo support require high-quality care and excellent surgical techniques as well as advanced methods of postoperative care. These techniques are constantly being updated and new methods are emerging.We report results of our double steel-wire closure technique in large bovine models used for Cleveland Clinic's continuous-flow total artificial heart development program. This is the first report of double-wire sternal fixation used in large bovine models.
doi_str_mv 10.5301/ijao.5000426
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source MEDLINE; SAGE Complete A-Z List
subjects Animals
Artificial organs
Cattle
Circulation
Devices
Heart, Artificial
In vivo methods and tests
In vivo testing
In vivo tests
Models, Animal
Sternotomy
Sternum - surgery
Surgical implants
Suture Techniques
title Double-wire sternal closure technique in bovine animal models for total artificial heart implant
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