Bioactive treatment promotes osteoblast differentiation on titanium materials fabricated by selective laser melting technology

Selective laser melting (SLM) technology is useful for the fabrication of porous titanium implants with complex shapes and structures. The materials fabricated by SLM characteristically have a very rough surface (average surface roughness, Ra=24.58 µm). In this study, we evaluated morphologically an...

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Veröffentlicht in:Dental Materials Journal 2016/01/29, Vol.35(1), pp.118-125
Hauptverfasser: TSUKANAKA, Masako, FUJIBAYASHI, Shunsuke, TAKEMOTO, Mitsuru, MATSUSHITA, Tomiharu, KOKUBO, Tadashi, NAKAMURA, Takashi, SASAKI, Kiyoyuki, MATSUDA, Shuichi
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container_end_page 125
container_issue 1
container_start_page 118
container_title Dental Materials Journal
container_volume 35
creator TSUKANAKA, Masako
FUJIBAYASHI, Shunsuke
TAKEMOTO, Mitsuru
MATSUSHITA, Tomiharu
KOKUBO, Tadashi
NAKAMURA, Takashi
SASAKI, Kiyoyuki
MATSUDA, Shuichi
description Selective laser melting (SLM) technology is useful for the fabrication of porous titanium implants with complex shapes and structures. The materials fabricated by SLM characteristically have a very rough surface (average surface roughness, Ra=24.58 µm). In this study, we evaluated morphologically and biochemically the specific effects of this very rough surface and the additional effects of a bioactive treatment on osteoblast proliferation and differentiation. Flat-rolled titanium materials (Ra=1.02 µm) were used as the controls. On the treated materials fabricated by SLM, we observed enhanced osteoblast differentiation compared with the flat-rolled materials and the untreated materials fabricated by SLM. No significant differences were observed between the flat-rolled materials and the untreated materials fabricated by SLM in their effects on osteoblast differentiation. We concluded that the very rough surface fabricated by SLM had to undergo a bioactive treatment to obtain a positive effect on osteoblast differentiation.
doi_str_mv 10.4012/dmj.2015-127
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source J-STAGE Free; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Animals
Bioactive treatment
Biochemistry
Biocompatibility
Biomedical materials
Cell Adhesion
Cell Differentiation
Cell Proliferation
Cells, Cultured
Culture Media - chemistry
Dental materials
Dentistry
Differentiation
Laser beam melting
Lasers
Materials selection
Materials Testing
Mice
Microscopy, Confocal
Microscopy, Electron, Scanning
Osteoblast differentiation
Osteoblasts - physiology
Real-Time Polymerase Chain Reaction
Selective laser melting technology
Surface Properties
Tetrazolium Salts
Titanium - chemistry
Titanium base alloys
Wettability
title Bioactive treatment promotes osteoblast differentiation on titanium materials fabricated by selective laser melting technology
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