Evaluation of Response of the Human Body to Changes in Choline Content in Food
Choline-containing preparations are used in the medical practice for treatment and prevention of the neurologic disorders of different genesis. We have used mathematical simulation to study the influence of the content of choline in the food ration of rats on the dynamics of the expression of nicoti...
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| Veröffentlicht in: | Biomedical engineering 2014-03, Vol.47 (6), p.323-327 |
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| creator | Gusev, V. B. Anokhin, A. M. Guseva, M. V. |
| description | Choline-containing preparations are used in the medical practice for treatment and prevention of the neurologic disorders of different genesis. We have used mathematical simulation to study the influence of the content of choline in the food ration of rats on the dynamics of the expression of nicotinic acetylcholine receptors of brain, as well as changes in the indices associated with the metabolism of choline in the organism – mass of the body of animals and amount of consumed food and water. The model was verified on the experimental data. The results of our work might be useful for developing a neuroprotection strategy based on the use of choline-containing preparations and minimizing the consequences of cerebral disorders after brain injury. |
| doi_str_mv | 10.1007/s10527-014-9402-9 |
| format | Article |
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The results of our work might be useful for developing a neuroprotection strategy based on the use of choline-containing preparations and minimizing the consequences of cerebral disorders after brain injury.</description><subject>Acetylcholine receptors (nicotinic)</subject><subject>Analysis</subject><subject>Biomaterials</subject><subject>Biomedical Engineering and Bioengineering</subject><subject>Brain</subject><subject>Brain injury</subject><subject>Choline</subject><subject>Disorders</subject><subject>Engineering</subject><subject>Food</subject><subject>Foods</subject><subject>Genesis</subject><subject>Head injuries</subject><subject>Human body</subject><subject>Mathematical models</subject><subject>Medical services</subject><subject>Neurobiology</subject><subject>Neuroprotection</subject><subject>Nutrition</subject><subject>Physiological aspects</subject><subject>Rations</subject><subject>Rodents</subject><subject>Vitamins</subject><issn>0006-3398</issn><issn>1573-8256</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFksFq3DAQhkVpodu0D9CboZfk4HRGY9nSMVk2TSC0kOYutPZ44-CVNpZdmrevzAaaLQnVHDQavn9gNL8QnxFOEaD6GhGUrHLAIjcFyNy8EQtUFeVaqvKtWABAmRMZ_V58iPE-PZXWciG-r365fnJjF3wW2uyG4y74yHM-3nF2OW2dz85D85iNIVveOb_hmHU-paHvPGfL4Ef241y6CKH5KN61ro_86ek-ErcXq9vlZX7949vV8uw6r0mByQ2VBtcNadUw6bVGh0YiyXULzkhdKwVSOmiooEazY1al0gQ1oeFCFXQkjvdtd0N4mDiOdtvFmvveeQ5TtKhBI5Rlpf-PVroySgPJhH75B70P0-DTHDOFSqZDf6mN69l2vg3j4Oq5qT0jTViVWJlEnb5ApWh429XBc9ul-oHg5EBQzx_7e9y4KUZ79fPmkMU9Ww8hxoFbuxu6rRseLYKd7WD3drDJDna2g501cq-JiU1bHJ4N96roD8wpsVg</recordid><startdate>20140301</startdate><enddate>20140301</enddate><creator>Gusev, V. 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| subjects | Acetylcholine receptors (nicotinic) Analysis Biomaterials Biomedical Engineering and Bioengineering Brain Brain injury Choline Disorders Engineering Food Foods Genesis Head injuries Human body Mathematical models Medical services Neurobiology Neuroprotection Nutrition Physiological aspects Rations Rodents Vitamins |
| title | Evaluation of Response of the Human Body to Changes in Choline Content in Food |
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