Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels

This paper reports a method for generating an intact and perfusable microvascular network that connects to microfluidic channels without appreciable leakage. This platform incorporates different stages of vascular development including vasculogenesis, endothelial cell (EC) lining, sprouting angiogen...

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Veröffentlicht in:	Lab on a chip 2016-01, Vol.16 (2), p.282-29
Hauptverfasser:	Wang, Xiaolin, Phan, Duc T. T, Sobrino, Agua, George, Steven C, Hughes, Christopher C. W, Lee, Abraham P
Format:	Artikel
Sprache:	eng
Schlagworte:	Anastomosis, Surgical Arteries Capillarity Cells, Cultured Channels Endothelial Cells - cytology Humans Interconnection Leakage Microfluidic Analytical Techniques - instrumentation Microfluidics Microvessels Neovascularization, Physiologic Networks Tissue Engineering Veins
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