A simple isotopic labeling method to study cysteine oxidation in Alzheimer’s disease: oxidized cysteine-selective dimethylation (OxcysDML)

Cysteine is widely involved in redox signaling pathways through a number of reversible and irreversible modifications. Reversible modifications (e.g., S-glutathionylation, S-nitrosylation, disulfide bonds, and sulfenic acid) are used to protect proteins from oxidative attack and maintain cellular ho...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Analytical and bioanalytical chemistry 2016-04, Vol.408 (11), p.2993-3004
Hauptverfasser:	Gu, Liqing, Robinson, Renã A. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - metabolism Alzheimer's disease Amino acids Analytical Chemistry Animals Biochemistry Characterization and Evaluation of Materials Chemical bonds Chemistry Chemistry and Materials Science Chromatography, Liquid Cysteine Cysteine - chemistry Enrichment Food Science Health aspects Homeostasis Humans Isotope analysis Isotope Labeling Isotopic labeling Labeling Laboratory Medicine Methods Methylation Mice Mice, Transgenic Monitoring/Environmental Analysis Observations Oxidation Oxidation-Reduction Oxidation-reduction reactions Oxidative stress Peptides Physiological aspects Proteins Proteomics Reagents Research Paper Tandem Mass Spectrometry Young Investigators in Analytical and Bioanalytical Science
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!