Probability density function of the electric field in diffuse correlation spectroscopy of human bone in vivo
Diffuse correlation spectroscopy (DCS) is the technique of choice for non-invasive assessments of human bone blood flow. However, DCS classical algorithms are based on the fundamental assumption that the electric field of the light reaching the DCS photodetector is a zero-mean complex Gaussian varia...
Gespeichert in:
| Veröffentlicht in: | Applied Optics 2016-02, Vol.55 (4), p.757-762 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 762 |
|---|---|
| container_issue | 4 |
| container_start_page | 757 |
| container_title | Applied Optics |
| container_volume | 55 |
| creator | Binzoni, Tiziano Sanguinetti, Bruno Van de Ville, Dimitri Zbinden, Hugo Martelli, Fabrizio |
| description | Diffuse correlation spectroscopy (DCS) is the technique of choice for non-invasive assessments of human bone blood flow. However, DCS classical algorithms are based on the fundamental assumption that the electric field of the light reaching the DCS photodetector is a zero-mean complex Gaussian variable. The non-validity of this hypothesis might produce inaccurate blood flow estimations. It is shown that for the human tibia, the "Gaussian hypothesis" holds for interoptode distances ≥20 mm. This lower boundary seems to depend on the type of investigated tissue. |
| doi_str_mv | 10.1364/AO.55.000757 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1808065858</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1808065858</sourcerecordid><originalsourceid>FETCH-LOGICAL-c324t-2f5f85e217c6e1ca8efd452b5b5ffee1d65e46e7c2492dc800b90b5818f87c513</originalsourceid><addsrcrecordid>eNqFkb1PwzAQxS0EoqWwMSOPDKTYTs52xgrxJVUqA8xR4pxVoyQOcVKp_z0JLaxMT3f6vSfdPUKuOVvyWCb3q80SYMkYU6BOyFxwgCjmEk7JfFzGkUxjmJGLED7HCZJUnZOZkDqWTKk5qd46X-SFq1y_pyU2YVI7NKZ3vqHe0n6LFCs0fecMtQ6rkrqGls7aISA1vuuwyn_g0E6UD8a3-8m5Heq8oYVvcHLs3M5fkjObVwGvjrogH0-P7w8v0Xrz_PqwWkcmFkkfCQtWAwqujERuco22TEAUUIC1iLyUgIlEZUSSitJoxoqUFaC5tloZ4PGC3B5y285_DRj6rHbBYFXlDfohZFwzzSRo0P-jSgqp9PTJBbk7oGY8MnRos7Zzdd7tM86yqYpstckAskMVI35zTB6KGss_-Pf38TelNYUl</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1762678000</pqid></control><display><type>article</type><title>Probability density function of the electric field in diffuse correlation spectroscopy of human bone in vivo</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><source>Optica Publishing Group Journals</source><creator>Binzoni, Tiziano ; Sanguinetti, Bruno ; Van de Ville, Dimitri ; Zbinden, Hugo ; Martelli, Fabrizio</creator><creatorcontrib>Binzoni, Tiziano ; Sanguinetti, Bruno ; Van de Ville, Dimitri ; Zbinden, Hugo ; Martelli, Fabrizio</creatorcontrib><description>Diffuse correlation spectroscopy (DCS) is the technique of choice for non-invasive assessments of human bone blood flow. However, DCS classical algorithms are based on the fundamental assumption that the electric field of the light reaching the DCS photodetector is a zero-mean complex Gaussian variable. The non-validity of this hypothesis might produce inaccurate blood flow estimations. It is shown that for the human tibia, the "Gaussian hypothesis" holds for interoptode distances ≥20 mm. This lower boundary seems to depend on the type of investigated tissue.</description><identifier>ISSN: 0003-6935</identifier><identifier>ISSN: 1559-128X</identifier><identifier>EISSN: 2155-3165</identifier><identifier>EISSN: 1539-4522</identifier><identifier>DOI: 10.1364/AO.55.000757</identifier><identifier>PMID: 26836077</identifier><language>eng</language><publisher>United States</publisher><subject>Blood flow ; Bone and Bones - physiology ; Bones ; Correlation ; Diffusion ; Electric fields ; Electricity ; Forearm - physiology ; Gaussian ; Human ; Humans ; Male ; Probability ; Spectroscopy ; Spectrum Analysis - methods ; Tibia - physiology</subject><ispartof>Applied Optics, 2016-02, Vol.55 (4), p.757-762</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c324t-2f5f85e217c6e1ca8efd452b5b5ffee1d65e46e7c2492dc800b90b5818f87c513</citedby><cites>FETCH-LOGICAL-c324t-2f5f85e217c6e1ca8efd452b5b5ffee1d65e46e7c2492dc800b90b5818f87c513</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26836077$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Binzoni, Tiziano</creatorcontrib><creatorcontrib>Sanguinetti, Bruno</creatorcontrib><creatorcontrib>Van de Ville, Dimitri</creatorcontrib><creatorcontrib>Zbinden, Hugo</creatorcontrib><creatorcontrib>Martelli, Fabrizio</creatorcontrib><title>Probability density function of the electric field in diffuse correlation spectroscopy of human bone in vivo</title><title>Applied Optics</title><addtitle>Appl Opt</addtitle><description>Diffuse correlation spectroscopy (DCS) is the technique of choice for non-invasive assessments of human bone blood flow. However, DCS classical algorithms are based on the fundamental assumption that the electric field of the light reaching the DCS photodetector is a zero-mean complex Gaussian variable. The non-validity of this hypothesis might produce inaccurate blood flow estimations. It is shown that for the human tibia, the "Gaussian hypothesis" holds for interoptode distances ≥20 mm. This lower boundary seems to depend on the type of investigated tissue.</description><subject>Blood flow</subject><subject>Bone and Bones - physiology</subject><subject>Bones</subject><subject>Correlation</subject><subject>Diffusion</subject><subject>Electric fields</subject><subject>Electricity</subject><subject>Forearm - physiology</subject><subject>Gaussian</subject><subject>Human</subject><subject>Humans</subject><subject>Male</subject><subject>Probability</subject><subject>Spectroscopy</subject><subject>Spectrum Analysis - methods</subject><subject>Tibia - physiology</subject><issn>0003-6935</issn><issn>1559-128X</issn><issn>2155-3165</issn><issn>1539-4522</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkb1PwzAQxS0EoqWwMSOPDKTYTs52xgrxJVUqA8xR4pxVoyQOcVKp_z0JLaxMT3f6vSfdPUKuOVvyWCb3q80SYMkYU6BOyFxwgCjmEk7JfFzGkUxjmJGLED7HCZJUnZOZkDqWTKk5qd46X-SFq1y_pyU2YVI7NKZ3vqHe0n6LFCs0fecMtQ6rkrqGls7aISA1vuuwyn_g0E6UD8a3-8m5Heq8oYVvcHLs3M5fkjObVwGvjrogH0-P7w8v0Xrz_PqwWkcmFkkfCQtWAwqujERuco22TEAUUIC1iLyUgIlEZUSSitJoxoqUFaC5tloZ4PGC3B5y285_DRj6rHbBYFXlDfohZFwzzSRo0P-jSgqp9PTJBbk7oGY8MnRos7Zzdd7tM86yqYpstckAskMVI35zTB6KGss_-Pf38TelNYUl</recordid><startdate>20160201</startdate><enddate>20160201</enddate><creator>Binzoni, Tiziano</creator><creator>Sanguinetti, Bruno</creator><creator>Van de Ville, Dimitri</creator><creator>Zbinden, Hugo</creator><creator>Martelli, Fabrizio</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7SP</scope><scope>7U5</scope><scope>8FD</scope><scope>H8D</scope><scope>L7M</scope></search><sort><creationdate>20160201</creationdate><title>Probability density function of the electric field in diffuse correlation spectroscopy of human bone in vivo</title><author>Binzoni, Tiziano ; Sanguinetti, Bruno ; Van de Ville, Dimitri ; Zbinden, Hugo ; Martelli, Fabrizio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c324t-2f5f85e217c6e1ca8efd452b5b5ffee1d65e46e7c2492dc800b90b5818f87c513</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Blood flow</topic><topic>Bone and Bones - physiology</topic><topic>Bones</topic><topic>Correlation</topic><topic>Diffusion</topic><topic>Electric fields</topic><topic>Electricity</topic><topic>Forearm - physiology</topic><topic>Gaussian</topic><topic>Human</topic><topic>Humans</topic><topic>Male</topic><topic>Probability</topic><topic>Spectroscopy</topic><topic>Spectrum Analysis - methods</topic><topic>Tibia - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Binzoni, Tiziano</creatorcontrib><creatorcontrib>Sanguinetti, Bruno</creatorcontrib><creatorcontrib>Van de Ville, Dimitri</creatorcontrib><creatorcontrib>Zbinden, Hugo</creatorcontrib><creatorcontrib>Martelli, Fabrizio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Electronics & Communications Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Aerospace Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Applied Optics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Binzoni, Tiziano</au><au>Sanguinetti, Bruno</au><au>Van de Ville, Dimitri</au><au>Zbinden, Hugo</au><au>Martelli, Fabrizio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Probability density function of the electric field in diffuse correlation spectroscopy of human bone in vivo</atitle><jtitle>Applied Optics</jtitle><addtitle>Appl Opt</addtitle><date>2016-02-01</date><risdate>2016</risdate><volume>55</volume><issue>4</issue><spage>757</spage><epage>762</epage><pages>757-762</pages><issn>0003-6935</issn><issn>1559-128X</issn><eissn>2155-3165</eissn><eissn>1539-4522</eissn><abstract>Diffuse correlation spectroscopy (DCS) is the technique of choice for non-invasive assessments of human bone blood flow. However, DCS classical algorithms are based on the fundamental assumption that the electric field of the light reaching the DCS photodetector is a zero-mean complex Gaussian variable. The non-validity of this hypothesis might produce inaccurate blood flow estimations. It is shown that for the human tibia, the "Gaussian hypothesis" holds for interoptode distances ≥20 mm. This lower boundary seems to depend on the type of investigated tissue.</abstract><cop>United States</cop><pmid>26836077</pmid><doi>10.1364/AO.55.000757</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-6935 |
| ispartof | Applied Optics, 2016-02, Vol.55 (4), p.757-762 |
| issn | 0003-6935 1559-128X 2155-3165 1539-4522 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1808065858 |
| source | MEDLINE; Alma/SFX Local Collection; Optica Publishing Group Journals |
| subjects | Blood flow Bone and Bones - physiology Bones Correlation Diffusion Electric fields Electricity Forearm - physiology Gaussian Human Humans Male Probability Spectroscopy Spectrum Analysis - methods Tibia - physiology |
| title | Probability density function of the electric field in diffuse correlation spectroscopy of human bone in vivo |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T15%3A55%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Probability%20density%20function%20of%20the%20electric%20field%20in%20diffuse%20correlation%20spectroscopy%20of%20human%20bone%20in%20vivo&rft.jtitle=Applied%20Optics&rft.au=Binzoni,%20Tiziano&rft.date=2016-02-01&rft.volume=55&rft.issue=4&rft.spage=757&rft.epage=762&rft.pages=757-762&rft.issn=0003-6935&rft.eissn=2155-3165&rft_id=info:doi/10.1364/AO.55.000757&rft_dat=%3Cproquest_cross%3E1808065858%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1762678000&rft_id=info:pmid/26836077&rfr_iscdi=true |