Biostability enhancement of oil core — polysaccharide multilayer shell via photoinitiator free thiol-ene ‘click’ reaction

We report on the preparation of nanocapsules completely made of natural biomaterials. A lipophilic core (soybean oil and egg lecithin as surfactant) is coated with a polysaccharides-based multilayer shell (glycol chitosan and heparin) covalently cross-linked. Polysaccharides, opportunely modified wi...

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Veröffentlicht in:	Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2016-06, Vol.142, p.281-289
Hauptverfasser:	Calcagno, Vincenzo, Vecchione, Raffaele, Sagliano, Angela, Carella, Antonio, Guarnieri, Daniela, Belli, Valentina, Raiola, Luca, Roviello, Antonio, Netti, Paolo A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkenes - chemistry Animals Biocompatible Materials - chemical synthesis Biocompatible Materials - pharmacology Biocompatible polymers Biomaterials Brain - cytology Cell Line Cell Survival - drug effects Chitosan Chitosan - chemistry Click Chemistry Covalence Crosslinking Emulsions Endothelial Cells - drug effects Glycol chitosan Glycols Heparin - chemistry Heparins Layer by layer Lecithins - chemistry Mice Multilayers Nanocapsules - chemistry Nanostructure Oil-in-water nanoemulsion Soybean Oil - chemistry Sulfhydryl Compounds - chemistry Surface-Active Agents - chemistry Thiol-ene click chemistry Thiolated chitosan Ultraviolet Rays
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