A Hybrid Parameter Estimation Algorithm for S-System Model of Gene Regulatory Networks

The reconstruction of a gene regulatory network expressed in terms of a S-system model may be accomplished by a simple task of parameter estimation. Empirical data indicate that biological gene networks are sparsely connected and the average number of upstream-regulators per gene is less than two, i...

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Veröffentlicht in:	The Journal of the astronautical sciences 2013-12, Vol.60 (3-4), p.559-576
Hauptverfasser:	Juang, Jer-Nan, Shiau, Steven J. H., Wu, Wesson
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerospace Technology and Astronautics Algorithms Engineering Genes Government regulations Mathematical analysis Mathematical Applications in the Physical Sciences Mathematical models Networks Optimization Parameter estimation Space Exploration and Astronautics Space Sciences (including Extraterrestrial Physics
Online-Zugang:	Volltext
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