Clinical and Research Considerations for Patients With Hypertensive Acute Heart Failure: A Consensus Statement from the Society of Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group

Abstract Management approaches for patients in the emergency department (ED) who present with acute heart failure (AHF) have largely focused on intravenous diuretics. Yet, the primary pathophysiologic derangement underlying AHF in many patients is not solely volume overload. Patients with hypertensi...

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Veröffentlicht in:	Journal of cardiac failure 2016-08, Vol.22 (8), p.618-627
Hauptverfasser:	Collins, Sean P., MD, MSc, Levy, Phillip D., MD, MPH, Martindale, Jennifer L., MD, Dunlap, Mark E., MD, Storrow, Alan B., MD, Pang, Peter S., MD, MSc, Albert, Nancy M., RN, PhD, Felker, G. Michael, MD, MS, Fermann, Gregory J., MD, Fonarow, Gregg C., MD, Givertz, Michael M., MD, Hollander, Judd E., MD, Lanfear, David J., MD, Lenihan, Daniel J., MD, Lindenfeld, JoAnn M., MD, Peacock, W. Frank, MD, Sawyer, Douglas B., MD, PhD, Teerlink, John R., MD, Butler, Javed, MD, MPH, MBA
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Biomedical Research Cardiovascular Consensus Disease Management Emergency Emergency Medicine - methods Heart failure Heart Failure - complications Heart Failure - therapy Humans Hypertension Hypertension - complications Hypertension - therapy Societies, Medical United States
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Zusammenfassung:	Abstract Management approaches for patients in the emergency department (ED) who present with acute heart failure (AHF) have largely focused on intravenous diuretics. Yet, the primary pathophysiologic derangement underlying AHF in many patients is not solely volume overload. Patients with hypertensive AHF (H-AHF) represent a clinical phenotype with distinct pathophysiologic mechanisms that result in elevated ventricular filling pressures. To optimize treatment response and minimize adverse events in this subgroup, we propose that clinical management be tailored to a conceptual model of disease based on these mechanisms. This consensus statement reviews the relevant pathophysiology, clinical characteristics, approach to therapy, and considerations for clinical trials in ED patients with H-AHF.
ISSN:	1071-9164 1532-8414
DOI:	10.1016/j.cardfail.2016.04.015