Pregnancy outcome and uterine fibroids
Myomas are observed in about 3–12% of pregnant women. Uterine fibroids may affect the outcome of pregnancy. The presence of myomas – in particular of myomas that distort the uterine cavity and larger intramural myomas – has been associated with infertility. In the case of pregnancy, it has been link...
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Veröffentlicht in: | Best practice & research. Clinical obstetrics & gynaecology 2016-07, Vol.34, p.74-84 |
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description | Myomas are observed in about 3–12% of pregnant women. Uterine fibroids may affect the outcome of pregnancy. The presence of myomas – in particular of myomas that distort the uterine cavity and larger intramural myomas – has been associated with infertility. In the case of pregnancy, it has been linked to an increased risk of spontaneous abortion, fetal malpresentation, placenta previa, preterm birth, cesarean section, and peripartum hemorrhage. Although fibroids may negatively affect pregnancy outcome, the impact of their treatment, particularly in quantitative terms, is unclear. Hysteroscopic myomectomy is the treatment of choice for submucous fibroids. The comparative efficacy of laparoscopic, laparotomic, or new modalities of treatment of intramural fibroids is not known. Up to date the choice and modalities of treatment of submucous fibroids should not be based on sound evidence but on clinical concerns and the skill of each center. |
doi_str_mv | 10.1016/j.bpobgyn.2015.11.017 |
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Uterine fibroids may affect the outcome of pregnancy. The presence of myomas – in particular of myomas that distort the uterine cavity and larger intramural myomas – has been associated with infertility. In the case of pregnancy, it has been linked to an increased risk of spontaneous abortion, fetal malpresentation, placenta previa, preterm birth, cesarean section, and peripartum hemorrhage. Although fibroids may negatively affect pregnancy outcome, the impact of their treatment, particularly in quantitative terms, is unclear. Hysteroscopic myomectomy is the treatment of choice for submucous fibroids. The comparative efficacy of laparoscopic, laparotomic, or new modalities of treatment of intramural fibroids is not known. 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All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c420t-46618ffc8bb974f5593823c86d3f533cb431d1632c4aebe0da7fe395ceb210c93</citedby><cites>FETCH-LOGICAL-c420t-46618ffc8bb974f5593823c86d3f533cb431d1632c4aebe0da7fe395ceb210c93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S152169341500231X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26723475$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Parazzini, Fabio, MD</creatorcontrib><creatorcontrib>Tozzi, Luca, MD</creatorcontrib><creatorcontrib>Bianchi, Stefano, MD</creatorcontrib><title>Pregnancy outcome and uterine fibroids</title><title>Best practice & research. Clinical obstetrics & gynaecology</title><addtitle>Best Pract Res Clin Obstet Gynaecol</addtitle><description>Myomas are observed in about 3–12% of pregnant women. Uterine fibroids may affect the outcome of pregnancy. The presence of myomas – in particular of myomas that distort the uterine cavity and larger intramural myomas – has been associated with infertility. In the case of pregnancy, it has been linked to an increased risk of spontaneous abortion, fetal malpresentation, placenta previa, preterm birth, cesarean section, and peripartum hemorrhage. Although fibroids may negatively affect pregnancy outcome, the impact of their treatment, particularly in quantitative terms, is unclear. Hysteroscopic myomectomy is the treatment of choice for submucous fibroids. The comparative efficacy of laparoscopic, laparotomic, or new modalities of treatment of intramural fibroids is not known. Up to date the choice and modalities of treatment of submucous fibroids should not be based on sound evidence but on clinical concerns and the skill of each center.</description><subject>Abortion, Spontaneous - epidemiology</subject><subject>Abruptio Placentae - epidemiology</subject><subject>Breech Presentation - epidemiology</subject><subject>Female</subject><subject>fibroids</subject><subject>Humans</subject><subject>Leiomyoma - pathology</subject><subject>Leiomyoma - surgery</subject><subject>miscarriage outcome treatment</subject><subject>Obstetrics and Gynecology</subject><subject>Postpartum Hemorrhage - epidemiology</subject><subject>Pregnancy</subject><subject>Pregnancy Complications - epidemiology</subject><subject>Pregnancy Outcome - epidemiology</subject><subject>Premature Birth - epidemiology</subject><subject>Tumor Burden</subject><subject>Uterine Myomectomy - methods</subject><subject>Uterine Neoplasms - pathology</subject><subject>Uterine Neoplasms - surgery</subject><issn>1521-6934</issn><issn>1532-1932</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtL7TAQx4Movj-CclbipjWTafrYeBHxBYKCCu5Ck04l5_Ykx6QVzre35Zzr4m5czSz-D-Y3jJ0AT4FDfjFP9dLrj5VLBQeZAqQcii22DxJFAhWK7WkXkOQVZnvsIMY554iVkLtsT-SFwKyQ--zsOdCHq51ZzfzQG7-gWe2a2dBTsI5mrdXB2yYesZ227iIdb-Yhe7u9eb2-Tx6f7h6urx4TkwneJ1meQ9m2ptS6KrJWygpLgabMG2wlotEZQgM5CpPVpIk3ddESVtKQFsBNhYfsfJ27DP5zoNirhY2Guq525IeooORFWfKqgFEq11ITfIyBWrUMdlGHlQKuJkRqrjaI1IRIAagR0eg73VQMekHNj-sfk1HwZy2g8dAvS0FFY8kZamwg06vG218rLv9LMJ111tTdX1pRnPshuJGiAhWF4upl-tP0JpCcC4R3_AZXjY4H</recordid><startdate>20160701</startdate><enddate>20160701</enddate><creator>Parazzini, Fabio, MD</creator><creator>Tozzi, Luca, MD</creator><creator>Bianchi, Stefano, MD</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20160701</creationdate><title>Pregnancy outcome and uterine fibroids</title><author>Parazzini, Fabio, MD ; Tozzi, Luca, MD ; Bianchi, Stefano, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c420t-46618ffc8bb974f5593823c86d3f533cb431d1632c4aebe0da7fe395ceb210c93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Abortion, Spontaneous - epidemiology</topic><topic>Abruptio Placentae - epidemiology</topic><topic>Breech Presentation - epidemiology</topic><topic>Female</topic><topic>fibroids</topic><topic>Humans</topic><topic>Leiomyoma - pathology</topic><topic>Leiomyoma - surgery</topic><topic>miscarriage outcome treatment</topic><topic>Obstetrics and Gynecology</topic><topic>Postpartum Hemorrhage - epidemiology</topic><topic>Pregnancy</topic><topic>Pregnancy Complications - epidemiology</topic><topic>Pregnancy Outcome - epidemiology</topic><topic>Premature Birth - epidemiology</topic><topic>Tumor Burden</topic><topic>Uterine Myomectomy - methods</topic><topic>Uterine Neoplasms - pathology</topic><topic>Uterine Neoplasms - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Parazzini, Fabio, MD</creatorcontrib><creatorcontrib>Tozzi, Luca, MD</creatorcontrib><creatorcontrib>Bianchi, Stefano, MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Best practice & research. 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subjects | Abortion, Spontaneous - epidemiology Abruptio Placentae - epidemiology Breech Presentation - epidemiology Female fibroids Humans Leiomyoma - pathology Leiomyoma - surgery miscarriage outcome treatment Obstetrics and Gynecology Postpartum Hemorrhage - epidemiology Pregnancy Pregnancy Complications - epidemiology Pregnancy Outcome - epidemiology Premature Birth - epidemiology Tumor Burden Uterine Myomectomy - methods Uterine Neoplasms - pathology Uterine Neoplasms - surgery |
title | Pregnancy outcome and uterine fibroids |
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