Tooth loss might not alter molecular pathogenesis in an aged transgenic Alzheimer's disease model mouse

Background and objective Previous studies have reported that tooth loss is a risk factor of Alzheimer's disease (AD). However, the association between tooth loss and cognition and the impact of tooth loss on the molecular pathogenesis of AD remain elusive. In this study, we tested the effect of...

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Veröffentlicht in:	Gerodontology 2016-09, Vol.33 (3), p.308-314
Hauptverfasser:	Oue, Hiroshi, Miyamoto, Yasunari, Koretake, Katsunori, Okada, Shinsuke, Doi, Kazuya, Jung, Cha-Gyun, Michikawa, Makoto, Akagawa, Yasumasa
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Alzheimer Disease - pathology Alzheimer's disease amyloid-β Animals Dentistry Disease Models, Animal Hippocampus - cytology Learning Memory Mice Mice, Transgenic Tg2576 tooth loss Tooth Loss - pathology
Online-Zugang:	Volltext
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