Clinical significance of inflammatory mediators in the pathogenesis of oral cancer

Oral cancer has become a grave problem in many parts of the globe with two.thirds of the cases occurring in developing countries. Chronic inflammation plays a prominent role in the development of oral cancer. The rationale for molecular targeted prevention of oral cancer is promising. Therefore, the...

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Veröffentlicht in:	Journal of cancer research and therapeutics 2016-04, Vol.12 (2), p.447-457
Hauptverfasser:	Patel, Jayendrakumar, Shah, Franky, Joshi, Geeta, Patel, Prabhudas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Care and treatment Cell Transformation, Neoplastic - metabolism Curcumin - pharmacology Cytokines Cytokines - metabolism Development and progression DNA methylation Gene expression Gene Expression Regulation, Neoplastic Genetic aspects Health aspects Humans Inflammation - complications Inflammation - metabolism Inflammation Mediators - metabolism Kinases Mouth cancer Mouth Neoplasms - etiology Mouth Neoplasms - metabolism NF-kappa B - metabolism Nitric Oxide - metabolism Properties Reactive Oxygen Species - metabolism Signal Transduction - drug effects Squamous cell carcinoma Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - metabolism Vascular endothelial growth factor Vascular Endothelial Growth Factor A - metabolism
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