Rhodium/Yanphos-Catalyzed Asymmetric Interrupted Intramolecular Hydroaminomethylation of trans-1,2-Disubstituted Alkenes

The first interrupted asymmetric hydroaminomethylation reaction was developed. The challenging trans-1,2-disubstituted olefins were employed as substrates, and a series of valuable chiral pyrrolidinones and pyrrolidines were obtained in high yields with high regioselectivities and excellent enantios...

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Veröffentlicht in:	Journal of the American Chemical Society 2016-07, Vol.138 (29), p.9017-9020
Hauptverfasser:	Chen, Caiyou, Jin, Shicheng, Zhang, Zhefan, Wei, Biao, Wang, Heng, Zhang, Kai, Lv, Hui, Dong, Xiu-Qin, Zhang, Xumu
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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