Prognostic value of gray matter to white matter ratio in hypoxic and non-hypoxic cardiac arrest with non-cardiac etiology
Abstract Purpose This study evaluated the prognostic performance of the gray to white matter ratio (GWR) on brain computed tomography (CT) in out-of-hospital cardiac arrest (OHCA) survivors with a noncardiac etiology and compared the prognostic performance of GWR between hypoxic and nonhypoxic etiol...
Gespeichert in:
| Veröffentlicht in: | The American journal of emergency medicine 2016-08, Vol.34 (8), p.1583-1588 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1588 |
|---|---|
| container_issue | 8 |
| container_start_page | 1583 |
| container_title | The American journal of emergency medicine |
| container_volume | 34 |
| creator | Lee, Byung Kook, MD Kim, Won Young, MD Shin, Jonghwan, MD Oh, Joo Suk, MD Wee, Jung Hee, MD Cha, Kyoung Chul, MD Park, Yooseok, MD Choi, Jae Hyung, MD Jeung, Kyung Woon, MD |
| description | Abstract Purpose This study evaluated the prognostic performance of the gray to white matter ratio (GWR) on brain computed tomography (CT) in out-of-hospital cardiac arrest (OHCA) survivors with a noncardiac etiology and compared the prognostic performance of GWR between hypoxic and nonhypoxic etiologies. Methods Using a multicenter retrospective registry of adult OHCA patients treated with targeted temperature management, we identified those with a noncardiac etiology who underwent brain CT within 24 hours after restoration of spontaneous circulation. Attenuation of the gray matter and white matter (at the level of the basal ganglia, centrum semiovale, and high convexity) were measured and GWRs were calculated. The primary outcome was neurologic outcome. Results Of 164 patients, 145 (88.4%) were discharged with a poor neurologic outcome. Lower GWR was associated with a poor neurologic outcome. The sensitivities of this marker were markedly low (9.7%-43.5%) at cutoff values, with 100% sensitivity. The cutoff values of the GWR for hypoxic arrest showed higher sensitivities than those for nonhypoxic arrest. The area under the curve (AUC) values of the GWR for the caudate nucleus/posterior limb of the internal capsule, putamen/corpus callosum, and basal ganglia were significant in the hypoxic group, whereas the AUC of the putamen/corpus callosum was the only significant GWR in the nonhypoxic group. Conclusion A low GWR is associated with poor neurologic outcome in noncardiac etiology OHCA patients treated with targeted temperature management. Gray to white matter ratio can help to predict the neurologic outcome in a cardiac arrest with hypoxic etiology rather than a nonhypoxic etiology. |
| doi_str_mv | 10.1016/j.ajem.2016.05.063 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1807080651</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0735675716301966</els_id><sourcerecordid>1807080651</sourcerecordid><originalsourceid>FETCH-LOGICAL-c439t-90671f12ac925f18db2404f2cf2f18c25934d745591aad58071f93c7c4b1e7a23</originalsourceid><addsrcrecordid>eNp9klGL1DAQx4Mo3nr6BXyQgC--tGbSpmlBBDnUOzhQUJ9DNp3uprbNmqR39tub3t4q3INPyUx-_2Ey_yHkJbAcGFRv-1z3OOY83XMmclYVj8gGRMGzGiQ8JhsmC5FVUsgz8iyEnjGAUpRPyRmXXNaSw4YsX73bTS5Ea-iNHmakrqM7rxc66hjR0-jo7d5GPMVeR-uoneh-ObjfSaWnlk5uyk6x0b61OuW9xxDprY37u_dTHpN-cLvlOXnS6SHgi_vznPz49PH7xWV2_eXz1cWH68yURROzhlUSOuDaNFx0ULdbXrKy46bjKTJcNEXZylKIBrRuRc0S3RRGmnILKDUvzsmbY92Dd7_m1JIabTA4DHpCNwcFScJqVglI6OsHaO9mP6Xu7qhGpgGuFD9SxrsQPHbq4O2o_aKAqdUY1avVGLUao5hQyZgkenVfet6O2P6VnJxIwLsjgGkWNxa9CsbiZLC1Hk1UrbP_r__-gdwMdrJGDz9xwfDvHypwxdS3dTXWzYCqYNBUVfEHfsq0CQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1807970111</pqid></control><display><type>article</type><title>Prognostic value of gray matter to white matter ratio in hypoxic and non-hypoxic cardiac arrest with non-cardiac etiology</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Lee, Byung Kook, MD ; Kim, Won Young, MD ; Shin, Jonghwan, MD ; Oh, Joo Suk, MD ; Wee, Jung Hee, MD ; Cha, Kyoung Chul, MD ; Park, Yooseok, MD ; Choi, Jae Hyung, MD ; Jeung, Kyung Woon, MD</creator><creatorcontrib>Lee, Byung Kook, MD ; Kim, Won Young, MD ; Shin, Jonghwan, MD ; Oh, Joo Suk, MD ; Wee, Jung Hee, MD ; Cha, Kyoung Chul, MD ; Park, Yooseok, MD ; Choi, Jae Hyung, MD ; Jeung, Kyung Woon, MD ; for the Korean Hypothermia Network Investigators ; Korean Hypothermia Network Investigators</creatorcontrib><description>Abstract Purpose This study evaluated the prognostic performance of the gray to white matter ratio (GWR) on brain computed tomography (CT) in out-of-hospital cardiac arrest (OHCA) survivors with a noncardiac etiology and compared the prognostic performance of GWR between hypoxic and nonhypoxic etiologies. Methods Using a multicenter retrospective registry of adult OHCA patients treated with targeted temperature management, we identified those with a noncardiac etiology who underwent brain CT within 24 hours after restoration of spontaneous circulation. Attenuation of the gray matter and white matter (at the level of the basal ganglia, centrum semiovale, and high convexity) were measured and GWRs were calculated. The primary outcome was neurologic outcome. Results Of 164 patients, 145 (88.4%) were discharged with a poor neurologic outcome. Lower GWR was associated with a poor neurologic outcome. The sensitivities of this marker were markedly low (9.7%-43.5%) at cutoff values, with 100% sensitivity. The cutoff values of the GWR for hypoxic arrest showed higher sensitivities than those for nonhypoxic arrest. The area under the curve (AUC) values of the GWR for the caudate nucleus/posterior limb of the internal capsule, putamen/corpus callosum, and basal ganglia were significant in the hypoxic group, whereas the AUC of the putamen/corpus callosum was the only significant GWR in the nonhypoxic group. Conclusion A low GWR is associated with poor neurologic outcome in noncardiac etiology OHCA patients treated with targeted temperature management. Gray to white matter ratio can help to predict the neurologic outcome in a cardiac arrest with hypoxic etiology rather than a nonhypoxic etiology.</description><identifier>ISSN: 0735-6757</identifier><identifier>EISSN: 1532-8171</identifier><identifier>DOI: 10.1016/j.ajem.2016.05.063</identifier><identifier>PMID: 27278721</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Aged ; Brain research ; Cardiopulmonary resuscitation ; Cardiovascular disease ; Clinical outcomes ; Computed tomography ; Cooling ; Coronary vessels ; CPR ; Diabetes ; Drug overdose ; Emergency ; Emergency medical care ; Etiology ; Female ; Follow-Up Studies ; Gray Matter - diagnostic imaging ; Hospitals ; Humans ; Hypertension ; Hypothermia ; Hypoxia ; Hypoxia - blood ; Hypoxia - diagnosis ; Hypoxia - etiology ; Liver cirrhosis ; Male ; Medical imaging ; Middle Aged ; Mortality ; Neuroimaging - methods ; Out-of-Hospital Cardiac Arrest - blood ; Out-of-Hospital Cardiac Arrest - chemically induced ; Out-of-Hospital Cardiac Arrest - complications ; Prognosis ; Registries ; Retrospective Studies ; Studies ; Tomography, X-Ray Computed ; Traumatic brain injury ; White Matter - diagnostic imaging</subject><ispartof>The American journal of emergency medicine, 2016-08, Vol.34 (8), p.1583-1588</ispartof><rights>Elsevier Inc.</rights><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c439t-90671f12ac925f18db2404f2cf2f18c25934d745591aad58071f93c7c4b1e7a23</citedby><cites>FETCH-LOGICAL-c439t-90671f12ac925f18db2404f2cf2f18c25934d745591aad58071f93c7c4b1e7a23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0735675716301966$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27278721$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Byung Kook, MD</creatorcontrib><creatorcontrib>Kim, Won Young, MD</creatorcontrib><creatorcontrib>Shin, Jonghwan, MD</creatorcontrib><creatorcontrib>Oh, Joo Suk, MD</creatorcontrib><creatorcontrib>Wee, Jung Hee, MD</creatorcontrib><creatorcontrib>Cha, Kyoung Chul, MD</creatorcontrib><creatorcontrib>Park, Yooseok, MD</creatorcontrib><creatorcontrib>Choi, Jae Hyung, MD</creatorcontrib><creatorcontrib>Jeung, Kyung Woon, MD</creatorcontrib><creatorcontrib>for the Korean Hypothermia Network Investigators</creatorcontrib><creatorcontrib>Korean Hypothermia Network Investigators</creatorcontrib><title>Prognostic value of gray matter to white matter ratio in hypoxic and non-hypoxic cardiac arrest with non-cardiac etiology</title><title>The American journal of emergency medicine</title><addtitle>Am J Emerg Med</addtitle><description>Abstract Purpose This study evaluated the prognostic performance of the gray to white matter ratio (GWR) on brain computed tomography (CT) in out-of-hospital cardiac arrest (OHCA) survivors with a noncardiac etiology and compared the prognostic performance of GWR between hypoxic and nonhypoxic etiologies. Methods Using a multicenter retrospective registry of adult OHCA patients treated with targeted temperature management, we identified those with a noncardiac etiology who underwent brain CT within 24 hours after restoration of spontaneous circulation. Attenuation of the gray matter and white matter (at the level of the basal ganglia, centrum semiovale, and high convexity) were measured and GWRs were calculated. The primary outcome was neurologic outcome. Results Of 164 patients, 145 (88.4%) were discharged with a poor neurologic outcome. Lower GWR was associated with a poor neurologic outcome. The sensitivities of this marker were markedly low (9.7%-43.5%) at cutoff values, with 100% sensitivity. The cutoff values of the GWR for hypoxic arrest showed higher sensitivities than those for nonhypoxic arrest. The area under the curve (AUC) values of the GWR for the caudate nucleus/posterior limb of the internal capsule, putamen/corpus callosum, and basal ganglia were significant in the hypoxic group, whereas the AUC of the putamen/corpus callosum was the only significant GWR in the nonhypoxic group. Conclusion A low GWR is associated with poor neurologic outcome in noncardiac etiology OHCA patients treated with targeted temperature management. Gray to white matter ratio can help to predict the neurologic outcome in a cardiac arrest with hypoxic etiology rather than a nonhypoxic etiology.</description><subject>Adult</subject><subject>Aged</subject><subject>Brain research</subject><subject>Cardiopulmonary resuscitation</subject><subject>Cardiovascular disease</subject><subject>Clinical outcomes</subject><subject>Computed tomography</subject><subject>Cooling</subject><subject>Coronary vessels</subject><subject>CPR</subject><subject>Diabetes</subject><subject>Drug overdose</subject><subject>Emergency</subject><subject>Emergency medical care</subject><subject>Etiology</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gray Matter - diagnostic imaging</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Hypothermia</subject><subject>Hypoxia</subject><subject>Hypoxia - blood</subject><subject>Hypoxia - diagnosis</subject><subject>Hypoxia - etiology</subject><subject>Liver cirrhosis</subject><subject>Male</subject><subject>Medical imaging</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Neuroimaging - methods</subject><subject>Out-of-Hospital Cardiac Arrest - blood</subject><subject>Out-of-Hospital Cardiac Arrest - chemically induced</subject><subject>Out-of-Hospital Cardiac Arrest - complications</subject><subject>Prognosis</subject><subject>Registries</subject><subject>Retrospective Studies</subject><subject>Studies</subject><subject>Tomography, X-Ray Computed</subject><subject>Traumatic brain injury</subject><subject>White Matter - diagnostic imaging</subject><issn>0735-6757</issn><issn>1532-8171</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9klGL1DAQx4Mo3nr6BXyQgC--tGbSpmlBBDnUOzhQUJ9DNp3uprbNmqR39tub3t4q3INPyUx-_2Ey_yHkJbAcGFRv-1z3OOY83XMmclYVj8gGRMGzGiQ8JhsmC5FVUsgz8iyEnjGAUpRPyRmXXNaSw4YsX73bTS5Ea-iNHmakrqM7rxc66hjR0-jo7d5GPMVeR-uoneh-ObjfSaWnlk5uyk6x0b61OuW9xxDprY37u_dTHpN-cLvlOXnS6SHgi_vznPz49PH7xWV2_eXz1cWH68yURROzhlUSOuDaNFx0ULdbXrKy46bjKTJcNEXZylKIBrRuRc0S3RRGmnILKDUvzsmbY92Dd7_m1JIabTA4DHpCNwcFScJqVglI6OsHaO9mP6Xu7qhGpgGuFD9SxrsQPHbq4O2o_aKAqdUY1avVGLUao5hQyZgkenVfet6O2P6VnJxIwLsjgGkWNxa9CsbiZLC1Hk1UrbP_r__-gdwMdrJGDz9xwfDvHypwxdS3dTXWzYCqYNBUVfEHfsq0CQ</recordid><startdate>20160801</startdate><enddate>20160801</enddate><creator>Lee, Byung Kook, MD</creator><creator>Kim, Won Young, MD</creator><creator>Shin, Jonghwan, MD</creator><creator>Oh, Joo Suk, MD</creator><creator>Wee, Jung Hee, MD</creator><creator>Cha, Kyoung Chul, MD</creator><creator>Park, Yooseok, MD</creator><creator>Choi, Jae Hyung, MD</creator><creator>Jeung, Kyung Woon, MD</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20160801</creationdate><title>Prognostic value of gray matter to white matter ratio in hypoxic and non-hypoxic cardiac arrest with non-cardiac etiology</title><author>Lee, Byung Kook, MD ; Kim, Won Young, MD ; Shin, Jonghwan, MD ; Oh, Joo Suk, MD ; Wee, Jung Hee, MD ; Cha, Kyoung Chul, MD ; Park, Yooseok, MD ; Choi, Jae Hyung, MD ; Jeung, Kyung Woon, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c439t-90671f12ac925f18db2404f2cf2f18c25934d745591aad58071f93c7c4b1e7a23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Brain research</topic><topic>Cardiopulmonary resuscitation</topic><topic>Cardiovascular disease</topic><topic>Clinical outcomes</topic><topic>Computed tomography</topic><topic>Cooling</topic><topic>Coronary vessels</topic><topic>CPR</topic><topic>Diabetes</topic><topic>Drug overdose</topic><topic>Emergency</topic><topic>Emergency medical care</topic><topic>Etiology</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Gray Matter - diagnostic imaging</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Hypothermia</topic><topic>Hypoxia</topic><topic>Hypoxia - blood</topic><topic>Hypoxia - diagnosis</topic><topic>Hypoxia - etiology</topic><topic>Liver cirrhosis</topic><topic>Male</topic><topic>Medical imaging</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Neuroimaging - methods</topic><topic>Out-of-Hospital Cardiac Arrest - blood</topic><topic>Out-of-Hospital Cardiac Arrest - chemically induced</topic><topic>Out-of-Hospital Cardiac Arrest - complications</topic><topic>Prognosis</topic><topic>Registries</topic><topic>Retrospective Studies</topic><topic>Studies</topic><topic>Tomography, X-Ray Computed</topic><topic>Traumatic brain injury</topic><topic>White Matter - diagnostic imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Byung Kook, MD</creatorcontrib><creatorcontrib>Kim, Won Young, MD</creatorcontrib><creatorcontrib>Shin, Jonghwan, MD</creatorcontrib><creatorcontrib>Oh, Joo Suk, MD</creatorcontrib><creatorcontrib>Wee, Jung Hee, MD</creatorcontrib><creatorcontrib>Cha, Kyoung Chul, MD</creatorcontrib><creatorcontrib>Park, Yooseok, MD</creatorcontrib><creatorcontrib>Choi, Jae Hyung, MD</creatorcontrib><creatorcontrib>Jeung, Kyung Woon, MD</creatorcontrib><creatorcontrib>for the Korean Hypothermia Network Investigators</creatorcontrib><creatorcontrib>Korean Hypothermia Network Investigators</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of emergency medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Byung Kook, MD</au><au>Kim, Won Young, MD</au><au>Shin, Jonghwan, MD</au><au>Oh, Joo Suk, MD</au><au>Wee, Jung Hee, MD</au><au>Cha, Kyoung Chul, MD</au><au>Park, Yooseok, MD</au><au>Choi, Jae Hyung, MD</au><au>Jeung, Kyung Woon, MD</au><aucorp>for the Korean Hypothermia Network Investigators</aucorp><aucorp>Korean Hypothermia Network Investigators</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic value of gray matter to white matter ratio in hypoxic and non-hypoxic cardiac arrest with non-cardiac etiology</atitle><jtitle>The American journal of emergency medicine</jtitle><addtitle>Am J Emerg Med</addtitle><date>2016-08-01</date><risdate>2016</risdate><volume>34</volume><issue>8</issue><spage>1583</spage><epage>1588</epage><pages>1583-1588</pages><issn>0735-6757</issn><eissn>1532-8171</eissn><abstract>Abstract Purpose This study evaluated the prognostic performance of the gray to white matter ratio (GWR) on brain computed tomography (CT) in out-of-hospital cardiac arrest (OHCA) survivors with a noncardiac etiology and compared the prognostic performance of GWR between hypoxic and nonhypoxic etiologies. Methods Using a multicenter retrospective registry of adult OHCA patients treated with targeted temperature management, we identified those with a noncardiac etiology who underwent brain CT within 24 hours after restoration of spontaneous circulation. Attenuation of the gray matter and white matter (at the level of the basal ganglia, centrum semiovale, and high convexity) were measured and GWRs were calculated. The primary outcome was neurologic outcome. Results Of 164 patients, 145 (88.4%) were discharged with a poor neurologic outcome. Lower GWR was associated with a poor neurologic outcome. The sensitivities of this marker were markedly low (9.7%-43.5%) at cutoff values, with 100% sensitivity. The cutoff values of the GWR for hypoxic arrest showed higher sensitivities than those for nonhypoxic arrest. The area under the curve (AUC) values of the GWR for the caudate nucleus/posterior limb of the internal capsule, putamen/corpus callosum, and basal ganglia were significant in the hypoxic group, whereas the AUC of the putamen/corpus callosum was the only significant GWR in the nonhypoxic group. Conclusion A low GWR is associated with poor neurologic outcome in noncardiac etiology OHCA patients treated with targeted temperature management. Gray to white matter ratio can help to predict the neurologic outcome in a cardiac arrest with hypoxic etiology rather than a nonhypoxic etiology.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27278721</pmid><doi>10.1016/j.ajem.2016.05.063</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0735-6757 |
| ispartof | The American journal of emergency medicine, 2016-08, Vol.34 (8), p.1583-1588 |
| issn | 0735-6757 1532-8171 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1807080651 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Aged Brain research Cardiopulmonary resuscitation Cardiovascular disease Clinical outcomes Computed tomography Cooling Coronary vessels CPR Diabetes Drug overdose Emergency Emergency medical care Etiology Female Follow-Up Studies Gray Matter - diagnostic imaging Hospitals Humans Hypertension Hypothermia Hypoxia Hypoxia - blood Hypoxia - diagnosis Hypoxia - etiology Liver cirrhosis Male Medical imaging Middle Aged Mortality Neuroimaging - methods Out-of-Hospital Cardiac Arrest - blood Out-of-Hospital Cardiac Arrest - chemically induced Out-of-Hospital Cardiac Arrest - complications Prognosis Registries Retrospective Studies Studies Tomography, X-Ray Computed Traumatic brain injury White Matter - diagnostic imaging |
| title | Prognostic value of gray matter to white matter ratio in hypoxic and non-hypoxic cardiac arrest with non-cardiac etiology |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-16T10%3A13%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prognostic%20value%20of%20gray%20matter%20to%20white%20matter%20ratio%20in%20hypoxic%20and%20non-hypoxic%20cardiac%20arrest%20with%20non-cardiac%20etiology&rft.jtitle=The%20American%20journal%20of%20emergency%20medicine&rft.au=Lee,%20Byung%20Kook,%20MD&rft.aucorp=for%20the%20Korean%20Hypothermia%20Network%20Investigators&rft.date=2016-08-01&rft.volume=34&rft.issue=8&rft.spage=1583&rft.epage=1588&rft.pages=1583-1588&rft.issn=0735-6757&rft.eissn=1532-8171&rft_id=info:doi/10.1016/j.ajem.2016.05.063&rft_dat=%3Cproquest_cross%3E1807080651%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1807970111&rft_id=info:pmid/27278721&rft_els_id=S0735675716301966&rfr_iscdi=true |