Sensitization of Radiation or Gemcitabine-Based Chemoradiation Therapeutic Effect by Nimotuzumab in Pancreatic Cancer Cells

This study was performed to observe the effect of the combination of nimotuzumab with radiation or gemcitabine-based chemoradiation on antipancreatic cancer cell therapy. Pancreatic cancer cells (PANC-1) were treated with nimotuzumab alone or combined with radiation (2, 4, or 8 Gy), which was either...

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Veröffentlicht in:	Technology in cancer research & treatment 2016-06, Vol.15 (3), p.446-452
Hauptverfasser:	Gao, Chunzi, Wu, Xianzhen, Yan, Ying, Meng, Lingnan, Shan, Dan, Li, Ying, Han, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal, Humanized - pharmacology Antineoplastic Combined Chemotherapy Protocols - pharmacology Apoptosis Apoptosis - drug effects Apoptosis - radiation effects Cancer therapies Cell cycle Cell Cycle - drug effects Cell Line, Tumor Cell proliferation Cell Proliferation - drug effects Cell Proliferation - radiation effects Cell therapy Chemoradiotherapy Chemoradiotherapy - methods Chemotherapy Deoxycytidine - analogs & derivatives Deoxycytidine - pharmacology Gemcitabine Humans Immunotherapy Monoclonal antibodies Pancreatic cancer Pancreatic Neoplasms - pathology Radiation therapy Targeted cancer therapy
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